Midwest City, Oklahoma Clinical Trials

A listing of Midwest City, Oklahoma clinical trials actively recruiting patient volunteers.

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Found 39 clinical trials
Does Insulin Sensitivity Impact the Potential of Metformin to Slow Aging

Aging is the number one risk factor for the majority of chronic diseases. There are no pharmaceutical treatments to slow aging and prolong healthspan. The anti-diabetic drug metformin is considered a likely pharmaceutical candidate to slow aging. In this study, the investigators hypothesize that metformin treatment in subjects free of …

chronic disease
insulin
diabetes
niddm
insulin sensitivity
University of Oklahoma Health Sciences Center, Oklahoma Shared Clinical and Translational Resources
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

measurable disease
gene amplification
solid tumour
pembrolizumab
exhausted
Bolt Investigative Site
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

refractory hepatoblastoma
measurable disease
shake
autologous stem cell infusion
platelet count
University of Oklahoma Health Sciences Center
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma

This is a phase II open-label study investigating the efficacy, safety and pharmacokinetic(PK) properties of OKN-007 combined with temozolomide(TMZ) in patients with recurrent glioblastoma(GBM). All patients will have been previously treated with the standard-of-care treatment which includes surgical resection, radiation and chemotherapy, and in some cases treatment for recurrent disease. …

The University of Oklahoma
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
Assessment of N-95 Facemask for Use in COVID-19 Pandemic in Case of Shortage of Personal Protective Equipment

The purpose of this study is to assess the safety and efficiency of an assembled modified mask in protecting health care workers against Coronavirus in case of any personal protective equipment shortage. At least 20 healthy participants will be recruited to try the modified mask. The modified masks will be …

coronavirus infection
covid-19
Oklahoma City VA Health Care System
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Functional Intermuscular Reduction of Spasticity

Investigators will use muscular dry needling in the calf of one lower extremity, followed by treadmill training with functional electrical stimulation.

electrical stimulation
spasticity
dry needling
Oklahoma Medical Research Foundation
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Micra AV Transcatheter Pacing System Post-Approval Registry

Medtronic is sponsoring the Micra AV Registry using the Micra AV system for continued surveillance of chronic atrioventricular synchronous pacing as intended, through the collection of data based on routine clinical care practice, following commercial release. The Micra AV Registry is conducted within Medtronic's Product Surveillance Registry (PSR) platform.

The University of Oklahoma Health Sciences Center
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +38 other locations
Pharmacokinetics Pharmacodynamics and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to …

acute respiratory syndrome (sars)
SARS
Board of Regents of the University of Oklahoma
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +34 other locations
NCI COVID-19 in Cancer Patients NCCAPS Study

This study collects blood samples, medical information, and medical images from patients who are being treated for cancer and have a positive test for SARS CoV-2, the new coronavirus that causes the disease called COVID-19. Collecting blood samples, medical information, and medical images may help researchers determine how COVID-19 affects …

acute respiratory syndrome (sars)
monoclonal antibodies
cancer treatment
hematopoietic and lymphoid cell neoplasm
BRAF
University of Oklahoma Health Sciences Center
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +575 other locations