Midwest City, Oklahoma Clinical Trials

A listing of Midwest City, Oklahoma clinical trials actively recruiting patient volunteers.

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Found 42 clinical trials
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In this prospective cohort study, 250 patients with suspected or known CAD and at least one intermediate coronary lesion (50-70% stenosis) who had a NiFFR value greater than 0.80 underwent coronary computed tomography angiography (CCTA) with NiFFR assessment. Patients were followed for one year to monitor for MACE

Online studies
  • 0 views
  • 28 Aug, 2025
  • Online study
Shweta - Protein and Polycystic Ovary Syndrome (PCOS)  

Polycystic ovary syndrome (PCOS) is a significant public health problem and is one of the most common hormonal disturbances affecting women of reproductive age. Women with PCOS are often insulin resistant, increasing their risk for cardiometabolic health problems (e.g., type 2 diabetes, heart disease, high blood pressure, sleep apnea, anxiety, …

Accepts healthy volunteers
Online studies
  • 0 views
  • 24 Apr, 2026
  • Online study
Social & QoL Behaviors in Parkinson's Disease

Adults with Parkinson's Disease experience an array of challenges and changes in daily living, behaviors, and functioning throughout the progression of their condition. The investigators want to learn more about the effects of Parkinson's Disease on individuals' social behavior and quality of life (QoL) compared to people of the same …

Accepts healthy volunteers
Online studies
  • 0 views
  • 02 Apr, 2026
  • Online study
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

alzheimer's disease
apolipoprotein e4
mental state examination
Accepts healthy volunteers
mini-mental state examination
IPS Research Company
 (7.4 away) Contact site
  • 32 views
  • 20 Sep, 2024
  • +126 other locations
Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

The purpose of this study is to evaluate the efficacy and safety of lenvatinib and pembrolizumab in combination with TACE versus TACE plus oral and intravenous (IV) placebos in participants with incurable, non-metastatic hepatocellular carcinoma (HCC). The primary hypotheses are that pembrolizumab plus lenvatinib in combination with TACE is superior …

hepatocellular carcinoma metastatic
metastatic hepatocellular carcinoma
chemoembolization
hcv infection
hepatitis b
Stephenson Cancer Center ( Site 0745)
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +37 other locations
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

brain lesion
aubagio
teriflunomide
urine test
multiple sclerosis
Investigational Site Number 8400018
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +15 other locations
Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis (FREVIVA)  

The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the disability progression and the safety up to approximately 51 months administration of study intervention compared to placebo in male and female participants with nrSPMS (aged 18 to 60 years at …

Oklahoma Medical Research Foundation Site Number : 8400039
 (6.3 away)
  • 0 views
  • 04 Mar, 2025
  • +58 other locations
A Study of BI-1206 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors (KEYNOTE-A04)

Phase 1/2a Clinical Trial of BI-1206, a Monoclonal Antibody to CD32b (FcRIIB), in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors Previously Treated with Anti-PD-1 or Anti-PD-L1 Antibodies

monoclonal antibodies
antineoplastic
solid tumor
targeted therapy
cancer
Oklahoma University , Stephenson Cancer Center
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +7 other locations
Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow

This research is studying two surgical procedures in a large group of people to learn about how well these procedures work as a treatment for ulnar neuropathy at the elbow (UNE). Researchers want to see which surgery is more helpful for people with ulnar neuropathy. This research will determine if …

University of Oklahoma
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors

IMC-F106C is an immune-mobilizing T cell receptor against cancer (ImmTAC ) designed for the treatment of cancers positive for the tumor-associated antigen PRAME. This is a first-in-human trial designed to evaluate the safety and efficacy of IMC-F106C in adult patients who have the appropriate HLA-A2 tissue marker and whose cancer …

University of Oklahoma Peggy and Charles Stephenson Cancer Center
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations