Beachwood, Ohio Clinical Trials

A listing of Beachwood, Ohio clinical trials actively recruiting patient volunteers.

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Found 58 clinical trials
ELUCIDATE: Enabling LUng Cancer IDentification Using folATE Receptor Targeting

This is a phase 3, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary …

cancer
thoracoscopy
wedge excision
folic acid
wedge resection
Cleveland Clinic
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
ATR Inhibitor BAY 1895344 Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

The purpose of the study is to test how well patients with advanced solid tumors and ovarian cancer respond to treatment with BAY1895344 in combination with niraparib. In addition researchers want to find for patients the optimal dose of BAY1895344 in combination with niraparib, how the drug is tolerated and …

neutrophil count
cancer
ATR
primary peritoneal carcinoma
measurable disease
Cleveland Clinic
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

venetoclax
anaplastic lymphoma
cancer
solid tumor
measurable disease
University Hospitals Cleveland /ID# 212241
 (5.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +38 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

recurrent childhood rhabdomyosarcoma
graft versus host disease
hematopoietic growth factors
interferon
metastases
Cleveland Clinic Foundation
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
A Study of SGN-B6A in Advanced Solid Tumors

This trial will look at a drug called SGN-B6A to find out whether it is safe for people who have solid tumors. It will study SGN-B6A to find out what its side effects are. A side effect is anything the drug does besides treating cancer. It will also study whether …

bladder cancer
squamous cell carcinoma of head and neck
squamous cell carcinoma
cancer
breast cancer
Case Western Reserve University / University Hospitals Cleveland Medical Center
 (5.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation (TIRO-AF)

This is a single center randomized double blind controlled study of patients (BMI> 30 kg/m2) with obesity and Atrial Fibrillation (AFIB) randomized to Tirzepatide vs. placebo. It is expected that the significant weight loss with Tirzepatide will result in improved control, management, symptom severity, and burden of AFIB at 12 …

Cleveland Clinic
 (5.5 away) Contact site
  • 0 views
  • 31 Jan, 2025
  • 1 location
Reducing Stroke Risk in African-American Men

The project is a 6-month prospective Randomized Controlled Trial evaluating the effects of TargEted MAnageMent Intervention (TEAM, N=80) vs. wait-list (WL, N=80) control in African American men who have experienced a stroke or TIA within the past 5 years.

acute stroke
stroke
Case Western Reserve University
 (5.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

prostatic neoplasm
antiandrogens
taxane
cancer
docetaxel
Cleveland Clinic
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +21 other locations
Identification of Predictors for Clinical Outcomes in Femoroacetabular Impingement Surgery

The overarching goal of the study is to improve the surgical treatment outcomes of FAI, which is affecting an increasing number of military personnel and young active individuals in the general population. The proposed study will investigate critical patient, disease, and surgical treatment predictors of FAI surgery outcomes.

hip arthroscopy
femoroacetabular impingement
conservative management
arthroscopy
UH Cleveland (Case Western)
 (5.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +11 other locations
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

deficiency
eliglustat
gaucher disease
imiglucerase
Investigational Site Number 840048
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +220 other locations