Beachwood, Ohio Clinical Trials

A listing of Beachwood, Ohio clinical trials actively recruiting patient volunteers.

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Found 58 clinical trials
Study of SAR339375 in Patients With Alport Syndrome

Primary Objectives: To assess the efficacy of SAR339375 in reducing the decline in renal function To assess the safety and tolerability of SAR339375 Secondary Objectives: To assess plasma pharmacokinetic (PK) parameters of the parent compound and its metabolites To assess the immunogenicity of the SAR339375

Investigational Site Number 8400001
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +12 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
tirzepatide
body mass index
dulaglutide
Cleveland Clinic
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

adjuvant
cancer
platinum-based chemotherapy
immunomodulators
carboplatin
Research Site
 (9.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

mini-mental state examination
florbetapir
positron emission tomography
alzheimer's disease
flortaucipir
Rapid Medical Research Inc
 (1.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Primary Objective: To confirm appropriate dose levels of fitusiran when administered to male pediatric participants (ages 1 to <12 years of age) with severe hemophilia A or B Secondary Objective: To characterize the safety and tolerability To characterize the pharmacokinetics (PK)

antihemophilic factor
bethesda assay
fitusiran
haemophilia a
factor ix
Investigational Site Number 8400007
 (5.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +10 other locations
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Primary Objective: To confirm appropriate dose levels of fitusiran when administered to male pediatric participants (ages 1 to <12 years of age) with severe hemophilia A or B Secondary Objective: To characterize the safety and tolerability To characterize the pharmacokinetics (PK)

antihemophilic factor
bethesda assay
fitusiran
haemophilia a
factor ix
Investigational Site Number 8400007
 (5.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +10 other locations
Study of Lademirsen (SAR339375) in Patients With Alport Syndrome

Primary Objectives: To assess the efficacy of lademirsen (SAR339375) in reducing the decline in renal function To assess the safety and tolerability of lademirsen (SAR339375) in subjects with Alport syndrome Secondary Objectives: To assess plasma pharmacokinetic (PK) parameters of the parent compound and its metabolites To assess the potential formation …

The Cleveland Clinic Foundation_Investigational Site Number :8400001
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +22 other locations
Study of Lademirsen (SAR339375) in Patients With Alport Syndrome  

Primary Objectives: To assess the efficacy of lademirsen (SAR339375) in reducing the decline in renal function To assess the safety and tolerability of lademirsen (SAR339375) in subjects with Alport syndrome Secondary Objectives: To assess plasma pharmacokinetic (PK) parameters of the parent compound and its metabolites To assess the potential formation …

The Cleveland Clinic Foundation_Investigational Site Number :8400001
 (5.5 away)
  • 0 views
  • 01 Dec, 2025
  • +19 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

dementia
pick's disease
progranulin
aphasia
Case Western Reserve University
 (5.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +46 other locations
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away …

compression fracture
karnofsky performance status
renal cell carcinoma
sarcoma
mri spine
Cleveland Clinic Taussig Cancer Center
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location