a, a N Clinical Trials
A listing of a, a N clinical trials actively recruiting patients volunteers.
Found 1940 clinical trials
CCCG Relapsed Acute Lymphoblastic Leukemia 2017 Study in Children
There is little experience of using rituximab in pediatric ALL thus a CCCG Relapsed ALL 2017 Study will perform the study assessing the remission rate and MRD response of CD20+ ALL treated with rituximab.
- 0 views
- 19 Feb, 2024
- 1 location
Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) Before and During Treatment With Ocrelizumab
This is an open-label, multicenter study that includes a main study for all participants enrolled and an optional cerebrospinal fluid (CSF) sub-study. Self-identified African American (AA) and Hispanic or Latin American (HA) participants with a diagnosis of relapsing multiple sclerosis (RMS) will be enrolled.
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- 19 Feb, 2024
- 31 locations
Scripps Digital Diabetes: Cloud-Based Continuous Glucose Monitoring (CB CGM)
The Digital Dashboard facilitates real-time, remote monitoring of a large volume of patients simultaneously; automatically identifies and prioritizes patients for intervention; and will detect any and all potentially dangerous hypoglycemic episodes.
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- 19 Feb, 2024
- 1 location
change - Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic Sclerosis (TOP-N53-02)
Researchers will compare TOP-N53 solution in different strengths to a placebo (a look-alike substance that contains no drug) to see if TOP-N53 works to affect the aspects of the illness listed above.Participants will receive one or two treatments with the placebo or different strengths of TOP-N53.
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- 13 Jun, 2025
- 3 locations
Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic Sclerosis (TOP-N53-02)
Researchers will compare TOP-N53 solution in different strengths to a placebo (a look-alike substance that contains no drug) to see if TOP-N53 works to affect the aspects of the illness listed above.Participants will receive one or two treatments with the placebo or different strengths of TOP-N53.
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- 28 May, 2025
- 1 location
Efficacy and Safety of JMT101 Combined With Afatinib (or Osimertinib) in Patients With Non-Small Cell Lung Cancer
This study is a Phase Ib, open label, multi-center study of to evaluate the safety and efficacy of JMT101 combined with EGFR-TKIs (Afatinib or Osimertinib) in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring EGFR exon 20 insertion mutations.
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- 19 Feb, 2024
- 2 locations
Unannounced Meal Handling of Advanced Closed Loop Insulin Delivery in Monitored Condition
The study will follow participants for the periods of 3 months while using an advanced hybrid closed loop algorithm in free living conditions . Each period will have a different meal handling protocols. The objective is to identify the mitigation of the algorithm with different meal handling approaches.
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- 19 Feb, 2024
- 1 location
Non Fusion Surgery in Adolescent Idiopathic Scoliosis Patients
The primary objective of the study is to monitor the effectiveness of a minimal invasive non-fusion double rod bipolar posterior spinal implant (Nemost growing domino) to correct the scoliotic curve in growing patients suffering from progressive adolescent idiopathic scoliosis (AIS) who have failed conservative treatment.
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- 19 Feb, 2024
- 1 location
Transcutaneous Breast Cancer Diagnosis by Canine Odorology
Patient with an indication of interventional percutaneous procedure for characterization of a breast lesion, palpable or not, classified as category 4 or 5, according to the Breast Imaging (BI) Report and Data System of the American College of Radiology (RADS) classification detected at mammography and/or breast ultrasound examination.
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- 19 Feb, 2024
- 6 locations
Combining Cereals With Pulses - Reduced Gastrointestinal Symptoms?
The aim of the study is to compare self-reported gastrointestinal symptoms and intestinal fermentation rates of the study products as measured by breath hydrogen and methane in adult population with self-reported mild abdominal sensitivity to pulses. The study products are a pulse products with two different cereals.
- 0 views
- 19 Feb, 2024
- 1 location