a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 1959 clinical trials
All-trans Retinoic Acid (ATRA) in the Treatment of Recurrent/Metastatic Adenoid Cystic Carcinoma of the Head and Neck

This is a prospective, open-label, randomized controlled clinical intervention study to evaluate the efficacy and safety of all-trans retinoic acid (ATRA) in treating patients with recurrent metastatic adenoid cystic carcinoma of the head and neck.

metastatic adenoid cystic carcinoma
spiral computed tomography
tretinoin
measurable disease
carcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Locally-Advanced Breast Cancer

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

carcinoma
potassium
breast cancer staging
advanced breast cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Head and Neck Cancer

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

lymphadenopathy
chemoradiotherapy
external beam radiotherapy
head and neck cancer
electrolytes
  • 0 views
  • 19 Feb, 2024
  • 1 location
Metformin for Abdominal Aortic Aneurysm Growth Inhibition

A multi-centre population-based open-label randomized controlled trial with allocation concealment and blinded outcome assessment will examine if up to 2g metformin daily slows AAA growth in patients with small AAAs who do not have diabetes.

aaas
abdominal aortic aneurysm
metformin
aortic aneurysm
diabetes
  • 0 views
  • 19 Feb, 2024
  • 1 location
DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma

The primary objective of the trial is the safety and tolerability of administering a vaccine targeting the DNAJB1-PRKACA fusion kinase, in combination with nivolumab and ipilimumab in patients with unresectable or metastatic FLC and to assess the T-cell response.

hepatocellular carcinoma
ipilimumab
core needle biopsy
peptide vaccine
measurable disease
  • 0 views
  • 19 Feb, 2024
  • 1 location
The Study of IBI310 in Combination With IBI308 Compared to High-Dose Interferon In Patients With Acral Melanoma That Has Been Removed by Surgery

This is a phase III randomized, control, multi-center study of recombinant humanized anti-PD-1 mAb in combination with CTLA4 mAb for injection compared to high-Dose interferon in patients with acral melanoma that has been removed by surgery.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Clinical High and Genomic Low Hormone Receptor-positive Early Breast Cancer Patients With or Without Adjuvant Chemotherapy

A prospective, randomized, comparative study to evaluate efficacy of anticancer chemotherapy in predicting prognosis and determining chemotherapy method in early Hormone Receptor-positive breast cancer patients with clinicopathological high risk and GenesWell BCT low risk at multi-center in Korea

  • 0 views
  • 19 Feb, 2024
  • 1 location
PAXG Out in the Country

The objective of this study is to assess the reproducibility of PAXG regimen as first-line/primary chemotherapy in daily clinical practice in Pancreatic Ductal Adenocarcinoma (PDAC) borderline resectable, locally advanced or metastatic patients out of a large volume center.

resectable pancreatic ductal adenocarcinoma
paclitaxel
pdac
serum total bilirubin level
cisplatin
  • 0 views
  • 19 Feb, 2024
  • 30 locations
Study of CPI-006 as Immunotherapy for Hospitalized COVID-19 Patients

This Phase 1 single-dose, dose-escalation study is an open label trial evaluating the safety of CPI-006, a humanized monoclonal antibody targeting the CD73 cell-surface ectonucleotidase, as immunotherapy for stable hospitalized mild or moderately symptomatic COVID-19 patients.

covid-19
acute respiratory syndrome (sars)
monoclonal antibodies
SARS
oximetry
  • 0 views
  • 19 Feb, 2024
  • 2 locations
VARA (Virtual and Augmented Reality Applications in Rehabilitation): Motor Rehabilitation Protocol With GRAIL for Patients Affected by Hemiparesis

The main goal of the study is to verify the efficacy of the GRAIL system in respect to the walking pattern improvement in a population of hemiparetic subjects. In particular, the specific goals will be: increase in walking symmetry and a better distribution among the time of stance and swing.

hemiparesis
weakness
  • 0 views
  • 19 Feb, 2024
  • 1 location