Chemotherapy Clinical Trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 904 clinical trials
Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer

The BREAKFAST trial will evaluate the antitumor activity of combining cyclic fasting-mimicking diet (FMD), which reproduces the in vitro effects of glucose starvation, plus/minus metformin with standard preperative anthracycline-taxane chemotherapy in patients with stage I-III TNBC

triple negative breast cancer
male sterilization
potassium
metformin
conjugated bilirubin
  • 0 views
  • 19 Feb, 2024
  • 1 location
Combination Immunotherapy Targeting Sarcomas

The aim of this clinical trial is to assess the feasibility, safety and efficacy of a combination low dose chemotherapy and immunotherapy in patients who have sarcoma that is relapsed or late staged. Another goal of the study is to assess the safety and efficacy of the therapy that combines …

kidney function tests
recurrent sarcoma
immunosuppression
creatinine clearance rate
serum bilirubin level
  • 0 views
  • 19 Feb, 2024
  • 2 locations
CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

This phase II trial studies how well liposome-encapsulated daunorubicin-cytarabine (CPX-351) works in treating patients with secondary acute myeloid leukemia who are younger than 60 years old. Drugs used in chemotherapy, such as CPX-351, work in different ways to stop the growth of cancer cells, either by killing the cells, by …

acute myeloid leukemia
secondary acute myeloid leukemia
treatment related aml
plasma creatinine
acute myeloid leukemia with myelodysplasia-related changes
  • 0 views
  • 19 Feb, 2024
  • 1 location
Organ Preservation Program Using Short-Course Radiation & FOLFOXIRI in Rectal Cancer

The purpose of the research is to evaluate whether both chemotherapy and radiotherapy can lead to higher rates of clinical complete response leading to organ preservation in human subjects with cancer.

adenocarcinoma
mri pelvis
blood transfusion
adenocarcinoma of rectum
organ preservation
  • 0 views
  • 19 Feb, 2024
  • 1 location
Pilot Study of an Implantable Microdevice for Evaluating Drug Responses in Situ in Prostate Cancer

In this research study, is assessing the feasibility of using an MR-guided implantable microdevice to measure tumor response to chemotherapy and other clinically relevant drugs in participants that have prostate cancer and are scheduled for a radical prostatectomy. The name of the study intervention involved in this study is: Implantation …

prostatectomy
carcinoma
neutrophil count
  • 2 views
  • 19 Feb, 2024
  • 1 location
Cross-sectoral Collaboration in Multidisciplinary Treatment of Trauma-affected Refugees

The randomised controlled trial is comparing treatment as usual (TAU) comprising 10 sessions with a medical doctor (pharmacological treatment and psycho-education) and 16-21 sessions with a psychologist (manual-based cognitive behavioural therapy) with add-on of the social intervention.

cognitive therapy
behavior therapy
post-traumatic stress disorder
violence
stress disorders
  • 0 views
  • 19 Feb, 2024
  • 1 location
Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma

All patients will have been previously treated with the standard-of-care treatment which includes surgical resection, radiation and chemotherapy, and in some cases treatment for recurrent disease. Patients with unequivocal recurrence (first or greater) established by MRI and meeting inclusion and exclusion criteria, will be eligible for OKN-007 treatment on this …

  • 0 views
  • 19 Feb, 2024
  • 3 locations
Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

Background Glioblastoma is a type of brain cancer. Treatments include radiation, chemotherapy, and surgery. But survival rates are poor. Researchers think that the drug selinexor, when combined with chemotherapy and radiation, might help.

glioblastoma multiforme
brain tumor
blood transfusion
gliosarcoma
blood tests
  • 0 views
  • 19 Feb, 2024
  • 1 location
AcceleRET Lung Study of Pralsetinib for 1L RET Fusion-positive Metastatic NSCLC

This is an international, randomized, open-label, Phase 3 study designed to evaluate whether the potent and selective RET inhibitor, pralsetinib, improves outcome when compared to a platinum chemotherapy-based regimen chosen by the Investigator from a list of standard of care treatments, as measured primarily by progression free survival (PFS), for …

adenocarcinoma
respiratory tract diseases
head and neck neoplasms
progressive disease
carcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Acalabrutinib Lenalidomide and Rituximab for the Treatment of CD20 Positive Stage III-IV Grade 1-3a Follicular Lymphoma

Acalabrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as lenalidomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them …

lenalidomide
oral contraceptives
international normalized ratio
tumor cells
follicular lymphoma, grade 1
  • 0 views
  • 19 Feb, 2024
  • 1 location