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Found 1 clinical trials
Topotecan Episcleral Plaque for Treatment of Retinoblastoma

This single site, single-arm, non-randomized, dose escalation phase I toxicity clinical trial will assess primarily the safety and secondarily the efficacy of episcleral topotecan in patients with active residual or recurrent intraocular retinoblastoma in at least one eye following completion of first-line therapy.

intraocular retinoblastoma
renal function
topotecan
platelet count
brachytherapy
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  • 19 Feb, 2024