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Found 3 clinical trials
Anti-GITR/Anti-PD1/Stereotactic Radiosurgery in Recurrent Glioblastoma

This is a phase II study of the combination of the GITR agonist monoclonal antibody INCAGN01876, the anti-PD1 monoclonal antibody INCMGA00012, and stereotactic radiosurgery (SRS) for recurrent Glioblastoma (GBM). The investigators hypothesize that the proposed regimen will be safe and stimulate a robust anti-tumor immune response and result in improved …

monoclonal antibodies
brain surgery
absolute lymphocyte count
recurrent tumor
gliadel
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  • 19 Feb, 2024
Phase 2 Trial in Multiple Brain Metastases Outcomes With HA-SIB-WBRT

There is however often poor tumour control with this technique due to the low doses given. Stereotactic Radiosurgery (SRS), a form of focused radiotherapy which is given to patients who have a limited number of brain metastases, gives a higher radiation dose to the metastases resulting in better target lesion …

metastasis
brain metastasis
stereotactic radiosurgery
whole brain radiotherapy
cancer
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  • 19 Feb, 2024
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away …

compression fracture
neurologic symptoms
relieve pain
metastasis
renal cell carcinoma
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  • 19 Feb, 2024