Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 7 clinical trials
Phase Study of the HS-10241 in Patients With Advanced Solid Tumors

HS-10241 is a highly potent and selective small molecule inhibitor of c-Met kinase. In preclinical studies, it demonstrated strong activity against c-Met kinase in vitro and in vivo, and inhibited tumor cell growth.

tubal ligation
solid neoplasm
ct scan
solid tumor
melanoma
  • 0 views
  • 19 Feb, 2024
Dose De-escalation Study of the PI3k Alpha/Delta Inhibitor Copanlisib Given in Combination With the Immunotherapeutic Agents Nivolumab and Rituximab in Patients With Relapsed/Refractory Indolent Lymphoma

Patients with relapsed or refractory follicular or marginal zone lymphoma who have received at least one prior line of therapy will receive Copanlisib IV: day 1, 8, 15 every 28 days Nivolumab IV: Cycle 1 days 1 and 15; then day 1 only Rituximab IV: Cycle 1 days 1, 8, …

stem cell transplant
immunohistochemistry
lymphoma
malt
cirrhosis
  • 0 views
  • 19 Feb, 2024
Expanded Access of Omidubicel for Allogeneic Transplantation in Patients With Hematological Malignancies

Omidubicel is an investigational therapy for patients with high-risk hematologic malignancies.

allogeneic transplantation
hematologic malignancy
cancer
investigational treatment
  • 0 views
  • 19 Feb, 2024
Prediction of Therapeutic Response of Apatinib in Recurrent Gliomas

Apatinib, also known as YN968D1, is a small-molecule tyrosine kinase inhibitor (TKI) that selectively binds to and inhibits vascular endothelial growth factor receptor 2 (VEGFR-2).

tyrosine
liver metastasis
glioma
vegf
vascular endothelial growth factor
  • 0 views
  • 19 Feb, 2024
Comparative Effectiveness of Targeted Therapy in RA Patients

The objective of a multicenter prospective observational study is to compare effectiveness and safety of biologic disease-modifying antirheumatic drugs and small molecular inhibitors in patients with moderately to severely active rheumatoid arthritis patients who have had an inadequate response or intolerace to methotrexate.

methotrexate
tocilizumab
abatacept
tofacitinib
antirheumatics
  • 0 views
  • 19 Feb, 2024
Natural History of Medullary Thyroid Cancer to Inform Advanced Disease Management

This study utilizes a multi-institutional registry to describe the natural history of medullary thyroid cancer that has spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced) in understanding disease management. The goal of this study is to learn about how medullary …

cancer
carcinoma
medullary thyroid carcinoma
  • 0 views
  • 19 Feb, 2024
Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach

Metagenomic shotgun sequencing and bacterial messenger ribonucleic acid (mRNA) analysis will inform about metabolic potential and metabolic activity of the microbiota. Mass spectrometry will assess the small molecule content of stool and maternal milk samples. Network analysis will be used to assess the complex relationships between bacteria metabolic activities and …

microbiota
diabetes
placenta
hypertension
mass spectrometry
  • 0 views
  • 19 Feb, 2024