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Found 11 clinical trials
SBRT for Breast Cancer Oligometastases

It is preferred that the same imaging method that was used to originally detect the metastases be used in follow-up assessments. The first imaging for SBRT sites will be three months post SBRT and every three months for the first year, every 6 months for the second year, then annually.

cancer
sbrt
solid tumor
breast cancer
bone scan
  • 0 views
  • 19 Feb, 2024
Phase II Study for Combination of Camrelizumab and SBRT in the First-line Treatment for R/M HNSCC

This study is a prospective, single-center, open-label, phase II clinical study for patients with recurrent or metastatics quamous cell carcinoma of the head and neck.

blood transfusion
squamous cell carcinoma
anticoagulants
carcinoma
liver metastasis
  • 0 views
  • 19 Feb, 2024
PRAGMA (Prostate Radio Ablation Guided by Magnetic Resonance Imaging Acquisition) in Metastatic Prostate Cancer

Patients with metastatic prostate cancer can undergo MRI-guided prostate Stereotactic body radiation therapy (SBRT) without significant adverse events, similar to what has been reported for patients with localized prostate cancer. We hypothesize that prostate SBRT will be well-tolerated in metastatic prostate cancer patients, with quality of life outcomes similar to …

cancer
metastatic prostate cancer
prostate cancer
MRI
non-metastatic prostate cancer
  • 0 views
  • 19 Feb, 2024
CIMER: Combined Immunotherapies in Metastatic ER+ Breast Cancer

Patients receiving standard first line therapy for metastatic HR+ Breast cancer(BC) (letrozole+palbociclib) are randomly assigned to also receive Stereotactic Body Radiation Therapy(SBRT) to each metastatic lesion.

palbociclib
HER2
oophorectomy
direct bilirubin
er+ breast cancer
  • 0 views
  • 19 Feb, 2024
Metastasis-directed Therapy in Castration-refractory Prostate Cancer

The aim is to define the postponement of next line systemic treatment (NEST), by the use of metastasis-directed therapy in patients with oligoprogressive castration-refractory prostate cancer. This will be defined by the NEST-free survival. Furthermore the investigators will use 18F PSMA PET-CT as investigational imaging, to assess the predictive value …

prostate cancer
pet/ct
conventional imaging
enzalutamide
adenocarcinoma
  • 0 views
  • 19 Feb, 2024
Nivolumab Ipilimumab and Chemoradiation in Treating Patients With Locally Advanced Pancreatic Cancer.

Pancreatic ductal adenocarcinoma (PDAC) remains a dreadful disease due to its often advanced stage at diagnosis and poor sensitivity to chemotherapy. A locally unresectable tumor (locally advanced pancreatic cancer (LAPC)) is present in 30% of the cases and is defined as a surgically unresectable tumor encasing the adjacent arteries [celiac …

serum bilirubin level
immunosuppressant
chemotherapy regimen
gemcitabine
gilbert's syndrome
  • 0 views
  • 19 Feb, 2024
SBRT Versus Ablation for Perivascular Hepatocellular Carcinoma

This trial is a multi-center, phase III, randomized (1:1) clinical trial. The aim is to explore the efficacy and safety of SBRT for perivascular hepatocellular carcinoma, compared with RFA.

recurrent hepatocellular carcinoma
stereotactic body radiation therapy
hepatocellular carcinoma
carcinoma
radiofrequency ablation
  • 0 views
  • 19 Feb, 2024
SBRT Dose Escalation for Reirradiation of Inoperable Lung Lesions

Prospective phase I study to evaluate the maximum tolerated dose (MTD) of SBRT for thoracic re-irradiation. Dose limiting toxicity will be pneumonitis G3. The potential advantage of the dose escalation planned in this study is the delivery of an ablative dose to radically treat patients with inoperable local relapse, without …

non-small cell lung cancer
cancer
pneumonitis
small cell lung cancer
lung cancer
  • 0 views
  • 19 Feb, 2024
Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer

This is a single-arm Phase II clinical trial assessing the clinical efficacy of prostate specific membrane antigen (PSMA) PET/MR guided MR-LINAC based SBRT-SIB with planned accrual of 50 patients.

metastasis
stereotactic body radiation therapy
hbed-cc
adenocarcinoma of prostate
adenocarcinoma
  • 16 views
  • 19 Feb, 2024
Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer

This trial studies how well atezolizumab added to the usual radiation therapy works in treating patients with stage I-IIA non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow …

atezolizumab
monoclonal antibodies
lung cancer
carcinoma
non-small cell carcinoma
  • 0 views
  • 19 Feb, 2024