rucaparib Clinical Research Trials

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Found 2 clinical trials

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Efficacy and Safety of the Combination of Rucaparib (PARP Inhibitor) and Atezolizumab (Anti-PD-L1 Antibody) in Patients With DNA Repair-deficient or Platinum-sensitive Solid Tumors

The primary objective of the trial is to evaluate the antitumor activity of atezolizumab and rucaparib in patients with selected advanced solid tumors as measured by the Overall Response Rate

heparin

recurrent solid tumor

measurable disease

prostate cancer

estrogen

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19 Feb, 2024

A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer

Patients will be treated with the combination of copanlisib and rucaparib for as long as the patient does not have clinically significant progressive disease and/or unacceptable toxicity and/or as long as the investigator deems that the patient is benefiting from treatment.

castration-resistant prostate cancer

apalutamide

primary tumor

measurable disease

unconjugated hyperbilirubinemia

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19 Feb, 2024