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Found 12 clinical trials
Featured trial
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  • 19 Feb, 2024
Featured trial
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  • 19 Feb, 2024
Gas Tamponade for Prevention of Postoperative Vitreous Hemorrhage in Diabetics

Subjects undergo vitreous substitution with either SF6 gas or fluid during vitrectomy.

vitrectomy
vitreous hemorrhage
diabetes
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  • 19 Feb, 2024
Topotecan Episcleral Plaque for Treatment of Retinoblastoma

This single site, single-arm, non-randomized, dose escalation phase I toxicity clinical trial will assess primarily the safety and secondarily the efficacy of episcleral topotecan in patients with active residual or recurrent intraocular retinoblastoma in at least one eye following completion of first-line therapy.

intraocular retinoblastoma
brachytherapy
renal function
platelet count
topotecan
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  • 19 Feb, 2024
JSI-1187-01 Monotherapy and in Combination With Dabrafenib for Advanced Solid Tumors With MAPK Pathway Mutations

This is a Phase 1 study of JSI-1187 as monotherapy and in combination with dabrafenib for the treatment of advanced solid tumors with MAPK pathway mutations, including mutations that cause MAPK pathway hyperactivation.

ipilimumab
mek inhibitor
experimental therapy
solid neoplasm
cancer
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  • 19 Feb, 2024
Manhattan Vision Screening and Follow-Up Study

The investigators are conducting a 5-year prospective, cluster-randomized controlled trial, funded by the Centers for Disease Control (CDC), which provides vision screenings to underserved, vulnerable New York City residents living in affordable housing buildings in Harlem and Washington Heights.

vision screening
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  • 19 Feb, 2024
Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease

Background The retina is a thin layer of tissue at the back of the eye. Retinal disease usually reduces a person s mobility because it affects how he or she moves through familiar and unfamiliar environments.

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  • 19 Feb, 2024
Internal Limiting Membrane Peeling in Proliferative Diabetic Retinopathy

Subject/Participant Groups: Study Group: Subjects undergo internal limiting membrane (ILM) peeling during vitrectomy for the indication of tractional retinal detachment Control Group: Subjects do not undergo ILM peeling during vitrectomy for the indication of tractional retinal detachment

vitrectomy
proliferative diabetic retinopathy
internal limiting membrane peeling
diabetic retinopathy
diabetes
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  • 19 Feb, 2024
The Diabetic Retinopathy Screening Prevention and Control Program

The greatest harm of diabetes is various acute and chronic complications, especially diabetic retinopathy(DR), leading to extremely high rates of disability and blindness. Early screening, early diagnosis, and early treatment are the keys to maintaining vision in patients with DR.

type 2 diabetes mellitus
cushing's syndrome
diabetic retinopathy screening
diabetic retinopathy
blindness
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  • 19 Feb, 2024
Clinical and Genetic Analysis of ROP

Retinopathy of Prematurity (ROP) is a vascular disease affecting the retinas (back of the eye) of low birth weight infants. Although it can be treated effectively if diagnosed early, it continues to be a leading cause of childhood blindness in the United States and throughout the world.

genetic analysis
premature birth
prematurity
vascular disease
blindness
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  • 19 Feb, 2024