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Found 18 clinical trials
A Trial to Evaluate the Efficacy and Safety of RSVpreF in Infants Born to Women Vaccinated During Pregnancy.

This randomized, double-blinded, placebo-controlled Phase 3 study is designed to evaluate the efficacy and safety of maternal immunization with RSVpreF against medically attended lower respiratory tract illness (MA-LRTI) in infants.

prenatal
hepatitis b
syphilis test
antigen test
vaccination
  • 0 views
  • 19 Feb, 2024
Understanding Factors That Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine Receptors

The goal of this proposal is to test the overall hypothesis that e-cigarettes (ECs) provide efficient nicotine delivery to the brain and arterial blood in non-EC-nave smokers and e-cigarette users and that EC liquid characteristics modulate this effect. This study will test the hypothesis through complementary methods that include [ …

  • 0 views
  • 19 Feb, 2024
Randomised Evaluation of COVID-19 Therapy

RECOVERY is a randomised trial investigating whether treatment with either Lopinavir-Ritonavir, Hydroxychloroquine, Corticosteroids, Azithromycin, Convalescent plasma or Tocilizumab prevents death in patients with COVID-19.

immunoglobulin
immunoglobulins
igiv
lopinavir/ritonavir
aspirin
  • 0 views
  • 19 Feb, 2024
Endoscopic Sinus Surgery in Recurrent Acute Rhinosinusitis

The aim of this study is to find out if endoscopic sinus surgery improves the quality of life in patients suffering from recurrent acute rhinosinusitis. Our main outcome is the difference between the average change in disease-specific SNOT-22 quality of life questionnaire scores (from baseline to 5-6 months follow-up) between …

antibiotic therapy
congestion
rhinosinusitis
acute rhinosinusitis
antibiotics
  • 0 views
  • 19 Feb, 2024
A Study to Evaluate the Safety Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults

This study aims to evaluate the safety and reactogenicity profile after 1 and 2 dose administrations of CVnCoV at different dose levels.

acute respiratory syndrome (sars)
human chorionic gonadotropin (hcg)
periodic abstinence
vaccination
human chorionic gonadotropin
  • 0 views
  • 19 Feb, 2024
Wells and Enteric Disease Transmission Trial (WET - Trial)

The investigators are preparing to conduct the first household randomized controlled trial (RCT) to investigate whether consuming well water treated by ultraviolet light (UV) compared to consuming untreated private well water decreases the incidence of self-reported gastrointestinal illness and respiratory infections in children under 5. The investigators will collect illness …

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  • 19 Feb, 2024
Prospective Clinical Trial of Onlay-carrying Patients

To complete it, a complete clinical oral examination will be performed with oral mirrors, examination probes, joint paper, disposable gloves, masks, paper napkins, plastic cups, dental equipment lighting lamp, cold spray , photogrammed camera, including an intraoral scan to have a 3D file of the patient's condition on the day …

  • 0 views
  • 19 Feb, 2024
A Home-based Physical Activity Programme for Patients With Advanced Interstitial Lung Diseases (iLiFE)

Interstitial lung diseases (ILD) are a highly incapacitating group of chronic respiratory diseases, leading to disabling symptoms and impaired capacity to perform activities of daily living and health-related quality of life (HRQoL). It is known that people with ILD are highly inactive and sedentary, and in a severe stage of …

  • 0 views
  • 19 Feb, 2024
Novel Face Mask Sampling for COVID-19: A Diagnostic and Public Health Tool

The investigators have previously demonstrated the utility of this method in other respiratory infections, such as tuberculosis. This project aims to investigate the utility of mask-based sampling is a tool for the diagnosis and quantification of COVID-19 in breath and the implications in a healthcare setting using three cohorts of …

acute respiratory syndrome (sars)
respiratory tract infection
SARS
nasopharyngeal swab
tuberculosis
  • 0 views
  • 19 Feb, 2024
Cardiovascular Consequences After COVID-19

The occurrence of cardiovascular complications in SARS-CoV-2 infections appears to be more frequent than in other viral respiratory infections, probably due to a singular pathophysiology of this coronavirus. The lack of characterization of cardiovascular damages linked to Covid-19 could have medium and long-term consequences on the prognosis of patients.

  • 0 views
  • 19 Feb, 2024