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Found 3 clinical trials
A Study of PD-1/CTLA-4 Bispecific AK104 in Relapsed or Refractory Peripheral T-cell Lymphoma

The purpose of this study is to evaluate the efficacy and safety of AK104an anti- PD-1 and CTLA-4 bispecific antibody, in subjects with relapsed or refractory peripheral T cell lymphoma. The subject will receive AK104 450mg Q2W until unacceptable toxicity, confirmed disease progression, withdrawal of consent, or for a maximum …

peripheral t-cell lymphoma
refractory peripheral t-cell lymphoma
lymphoma
cancer
t-cell lymphoma
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  • 19 Feb, 2024
Lenalidomide in Combination With CHOP in Patients With Untreated PTCL

Previous study showed that single agent lenalidomide showed promising therapeutic activity in patients with relapsed or refractory PTCL. The investigators therefore design this phase II study to investigate the safety and efficacy of lenalidomide in combination with CHOP in patients with treatment-naive PTCL.

peripheral t-cell lymphoma
anaplastic large cell lymphoma
lenalidomide
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  • 19 Feb, 2024
Azacitidine Combined With Chidamide in the Treatment of Newly Diagnosed PTCL Unfit for Conventional Chemotherapy

This prospective, open-label, single-arm study will evaluate the efficacy and safety of azacitidine in combination with chidamide in treatment of newly diagnosed peripheral T-cell lymphoma unfit for conventional chemotherapy.

peripheral t-cell lymphoma
tucidinostat
lymphoma
measurable disease
pet/ct scan
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  • 19 Feb, 2024