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Found 21 clinical trials
High Risk ER+HER2- T1-2N0-1 Early Breast Cancer With Palbociclib Plus Endocrine Therapy(HIPEx)

This is a phase II, multi-center, single-arm, open-label trial to evaluate efficacy of palbociclib with endocrine therapy as adjuvant treatment in women with C-high/G-high risk ER-positive/HER2-negative T1-2N0-1 EBC(Early Breast Cancer)

HER2
cancer
her2/neu-negative breast cancer
breast cancer
endocrine therapy
  • 0 views
  • 19 Feb, 2024
Exploring the Clinical Application Value of CAIX-Targeted PET Imaging in Renal Cancer Patients

To evaluate the efficacy of targeted CAIX-specific probe PET imaging in the diagnosis and staging of kidney cancer, as well as to assess its role in prognosis prediction and treatment evaluation for kidney cancer.

Accepts healthy volunteers
  • 0 views
  • 05 May, 2025
Combination of PD-1 and VEGFR-2 Blockade for Advanced Hepatocellular Carcinoma

The aie of this clinical study is the safety and efficacy of combination therapy for HCC patients.

systemic chemotherapy
blood transfusion
HIV Infection
monoclonal protein
measurable disease
  • 0 views
  • 19 Feb, 2024
HER2-PREDICT: Translational Study of Tumor Samples From DS8201-A-U301 and DS8201-A-U302 Trials.

This is a multi-center, observational study. Patients who will participate, are participating or have participated in Daichi Sankyo INC sponsored Ds8201-A-U301 and Ds8201-A-U302 trials will be asked to participate to HER2-PREDICT study offering them a new informed consent. In order to identify mRNA ERBB2 levels, we will evaluate by gene …

erbb2
primary tumor
pleural effusion
HER2
breast tumor
  • 0 views
  • 19 Feb, 2024
Neoadjuvant RCT Versus CT for Patients With Locally Advanced Potentially Resectable Adenocarcinoma of the GEJ

This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing neoadjuvant radiochemotherapy with FLOT versus FLOT chemotherapy alone fr patients with locally advanced, potentially resectable adenocarcinoma of the gastroesophageal junction (GEJ)

flot
aptt
progestogen
estrogen
flot regimen
  • 0 views
  • 19 Feb, 2024
Hypofractionated Radiotherapy in Elderly Patients With Head & Neck Squamous Cell Carcinoma

The purpose of this research study is to investigate a shorter radiation treatment schedule for head and neck cancers in patients 70 years of age and older. Standard radiation treatment for head and neck patients normally requires that the patient travel to the hospital daily for 6-7 weeks to receive …

  • 0 views
  • 19 Feb, 2024
Multimodality Treatment in Stage III Non-small Cell Lung Cancer (NSCLC)

Resectable, locally advanced NSCLC with involvement of mediastinal lymph nodes (N2) is associated with a high risk of (systemic) recurrence despite neo-adjuvant chemotherapy. Neo-adjuvant immunotherapy is a promising additional treatment modality aiming at increasing local control and better tackling micrometastases at the time of radical local treatment. Radiotherapy is thought …

blood transfusion
measurable disease
treatment regimen
cancer
non-small cell lung cancer
  • 0 views
  • 19 Feb, 2024
Metastasis-directed Therapy in Castration-refractory Prostate Cancer

The aim is to define the postponement of next line systemic treatment (NEST), by the use of metastasis-directed therapy in patients with oligoprogressive castration-refractory prostate cancer. This will be defined by the NEST-free survival. Furthermore the investigators will use 18F PSMA PET-CT as investigational imaging, to assess the predictive value …

pet/ct
cancer
adenocarcinoma
enzalutamide
abiraterone
  • 0 views
  • 19 Feb, 2024
The Value of Palliative Primary Tumor Resection in Metastatic Colon Cancer

The aim of this trial is to evaluate the value of palliative primary tumor resection in colon cancer patients with initially unresectable metastases and a positive response to induction chemotherapy which depends on gene testing.

systemic chemotherapy
tumor resection
adenocarcinoma of colon
stage iv colon cancer
primary tumor
  • 0 views
  • 19 Feb, 2024
Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity

Participants are assigned to one of 8 cohorts based on their primary tumour type: breast, lung, gastrointestinal (GI), primary unknown, genitourinary (GU), sarcoma, gynecological, and 'other' cancer types.

atezolizumab
serum bilirubin
blood transfusion
absolute neutrophil count
aptt
  • 0 views
  • 19 Feb, 2024