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Found 3 clinical trials
Neoadjuvant Chemotherapy With or Without Metformin in Early Breast Cancer.

This study examines the immune effect of metformin in breast cancer patients treated with preoperative chemotherapy.

breast carcinoma
cancer
metformin
preoperative chemotherapy
breast cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Neoadjuvant RCT Versus CT for Patients With Locally Advanced Potentially Resectable Adenocarcinoma of the GEJ

This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing neoadjuvant radiochemotherapy with FLOT versus FLOT chemotherapy alone fr patients with locally advanced, potentially resectable adenocarcinoma of the gastroesophageal junction (GEJ)

hormonal contraception
fluorouracil
neutrophil count
kidney function test
adenocarcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer

Glucose starvation and metformin have synergistic antitumor effects that are mediated through the concomitant inhibition of glycolysis and mitochondrial oxidative phosphorylation. The BREAKFAST trial will evaluate the antitumor activity of combining cyclic fasting-mimicking diet (FMD), which reproduces the in vitro effects of glucose starvation, plus/minus metformin with standard preperative anthracycline-taxane …

hysterectomy
taxane
anthracyclines
localized disease
gene amplification
  • 0 views
  • 19 Feb, 2024
  • 1 location