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Found 25 clinical trials
The TAPS Trial - Fetoscopic Laser Surgery for Twin Anemia Polycythemia Sequence

This multicenter open-label randomized controlled trial is set up to evaluate the effect of fetoscopic laser surgery on the gestational age at birth for monochorionic twin pregnancies diagnosed with twin anemia-polycythemia sequence. Half op the patients will be treated with fetoscopic laser surgery, while the other half will be managed …

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  • 19 Feb, 2024
Physical Activity and Preterm Birth With Cervical Dynamics

this RCT is designed to investigate the influence of physical activity on the risk f preterm birth for women with cervical dynamics.

premature birth
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  • 19 Feb, 2024
Determinants of Neonatal Anemia in Women Carrying Multiples  

Maternal anemia is known to increase the risk of adverse birth outcomes including preterm birth and low birth weight. Moreover, the developing brain is increasingly recognized to be susceptible to Fe insufficiency in utero and growing data support that suboptimal Fe stores at birth are associated with long-term irreversible cognitive …

Accepts healthy volunteers
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  • 22 Feb, 2024
  • 2 locations
Premie DCD Imaging Intervention Study

This study will leverage a current longitudinal study of brain development in preterm children. In the Miller/Grunau Trajectories study, preterm children are returning for follow-up at 8-9 years. At this appointment, children undergo MRI and neurodevelopmental testing. Children who are identified with DCD at this appointment will be invited to …

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  • 19 Feb, 2024
Evaluation of an Early Support Programme in Orthophony

Prospective, interventionnal with minimal risks and constraints, multicentric, non-randomized, open study, to measure the impact of an early support programme in speech and language therapy for vulnerable children (PAPEV-ortho), in children born very prematurely or very hypotrophically, on the incidence of language and communication deficits at the corrected age of …

intrauterine growth retardation
premature birth
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  • 19 Feb, 2024
Prevention of Preterm Birth by Screening of the Consistency Index and Length of the Uterine Cervix in Women With a Single Pregnancy

Preterm birth (PTB) is the major cause of perinatal morbidity and mortality. Worldwide, about 15 million babies are born too soon every year, causing 1.1 million deaths, as well as shortand long-term disability in countless survivors.

progesterone
uterine cervix
premature birth
pregnancy preterm
transvaginal ultrasound
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  • 19 Feb, 2024
Use Of Nfant(R) Technology Feeding System For Infants Less Than 30 Weeks GA

The purpose of the study is to utilize the objective data provided by the nfant suite of products, along with current NICU visual assessment and cue-based feeding practices, in order to determine if feeding performance outcomes and clinical decision making for individualized feeding plans for premature infants born less than …

prematurity
premature birth
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  • 19 Feb, 2024
A Novel Parent Education Program for Early Intervention

One in ten infants born in the USA is born preterm before 37 weeks of gestation and 50% of those will have motor and cognitive delays requiring intervention at school age. Because existing assessments do not reliably identify motor and cognitive delays early in development, many infants born preterm do …

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  • 19 Feb, 2024
Doxapram Therapy in Preterm Infants (DOXA Trial)

Preterm infants often suffer from apnea of prematurity (AOP; a cessation of breathing) due to immaturity of the respiratory system. AOP can lead to oxygen shortage and a low heart rate which might harm the development of the newborn, especially the central nervous system.

apnea
off-label
pulmonary disease
mechanical ventilation
doxapram
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  • 19 Feb, 2024
Targeted Fortification of Donor Breast Milk in Preterm Infants

This study is a randomized controlled trial comparing standard fortification of donor breast milk to targeted fortification of donor breast milk in preterm infants. The purpose of the study is to determine if there is a benefit to target fortifying donor breast milk in the preterm population. The investigators hypothesize …

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  • 19 Feb, 2024