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Found 2 clinical trials
Jaktinib Hydrochloride for the Treatment of Ruxolitinib Intolerance of Myelofibrosis

This phase IIB, open-label, multicenter study evaluated the efficacy and safety of oral Jaktinib Dihydrochloride in Intermediate-risk and High-risk Myelofibrosis and Previously Treated With Ruxolitinib

myelofibrosis
absolute neutrophil count
extramedullary hematopoiesis
neutrophil count
red blood cell transfusion
  • 0 views
  • 19 Feb, 2024
Decitabine With Ruxolitinib or Fedratinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms

This phase II trial studies how well decitabine with ruxolitinib or fedratinib works before hematopoietic stem cell transplant in treating patients with accelerated/blast phase myeloproliferative neoplasms (tumors). Drugs used in chemotherapy, such as decitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, …

myelodysplastic/myeloproliferative neoplasms
myelofibrosis
secondary myelofibrosis
fedratinib
blood count
  • 0 views
  • 19 Feb, 2024