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Found 3 clinical trials
Does Insulin Sensitivity Impact the Potential of Metformin to Slow Aging

Pre- and post--intervention, subjects will complete a series of procedures to assess insulin sensitivity, glucose regulation, and biomarkers of aging. The same subjects will provide a skeletal muscle biopsy pre-- and post-intervention to assess the change in mitochondrial function and mitochondrial remodeling with and without metformin treatment.

insulin resistance
a 12
chronic disease
diabetes
insulin
  • 0 views
  • 19 Feb, 2024
Illusory Movements in Patients With Burns

Background. Large burns are the cause of extensive skeletal muscle devastation. The possibilities of rehabilitation of such patients are very limited, which contributes to the risk of metabolic failure and long-term musculoskeletal disorders. Illusory movements are a relatively new method of physiotherapy, which through functional proprioceptive stimulation enables the integration …

catabolic state
insulin resistance
insulin
musculoskeletal disorders
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  • 19 Feb, 2024
B3 for NMD: Bench to Bedside and Back

Sample and data collection at the Neuromuscular Center, The Ottawa Hospital may include blood, DNA, saliva, cerebrospinal fluid, urine and stool samples, skin or muscle biopsy, and routine diagnostic imaging studies such as electrodiagnostic studies, ultrasound, and magnetic resonance imaging.

spinal muscular atrophy
amyotrophic lateral sclerosis
muscle biopsy
myopathy
neuropathy
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  • 19 Feb, 2024