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Found 483 clinical trials
Featured trial
A Mobile Application for Telerehabilitation in Parkinson's Disease  

The purpose of this study is to determine if the 9zest app for Parkinson's disease is feasible, safe, and efficacious when used independently by individuals with Parkinson's disease.

brain stimulation
parkinson's disease
  • 20 views
  • 19 Feb, 2024
  • 1 location
Featured trial
Internet Intervention for Diabetes Distress.

Diabetes distress is a psychological phenomenon associated with the self-management of the disease and is characterized by feelings of anxiety, guilt, helplessness, defeat, and depression. Research suggests that internet-delivered interventions have the potential to increase people's ability to self-manage their symptoms, but whether they are effective is largely unknown. This …

Accepts healthy volunteers
  • 0 views
  • 19 Feb, 2024
  • 19 locations
Featured trial
v6.11_prescreener_study(please don't touch)

This study aims to investigate the effect of stress management, specifically the Pythagorean Self-Awareness Intervention, on telomere length in T-leukocytes of breast cancer patients after completing all treatments except hormonal therapy. The study involves self-referred questionnaires, hair cortisol collection, and blood material extraction.

Accepts healthy volunteers
  • 0 views
  • 19 Feb, 2024
  • 2 locations
A Study to Compare the Efficacy and Safety of a Combined Regimen of Venetoclax and Obinutuzumab Versus Fludarabine Cyclophosphamide and Rituximab (FCR)/ Bendamustine And Rituximab (BR) in FIT Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL) Without DEL (17P) or TP53 Mutation

This study will evaluate the efficacy and safety of venetoclax and obinutuzumab (VEN + G) compared with fludarabine + cyclophosphamide + rituximab or bendamustine + rituximab (FCR/BR) in FIT participants (FIT is defined by a cumulative illness rating scale [CIRS]/score of 6 and a normal creatinine clearance of 70 mL/min) …

cytopenia
lymphocytic leukemia
myelodysplastic syndrome
venetoclax
neutrophil count
  • 0 views
  • 19 Feb, 2024
MicroNet-covered Stent System for Stroke Prevention in All Comer Carotid Revascularization

All-comer study of unselected patients suitable for carotid artery revascularization to evaluate the feasibility, efficacy and safety of first line endovascular revasculariztion using MicroNet covered stent (CGuard) in the treatment of consecutive symptomatic and increased-stroke-risk asymptomatic carotid lesions that require revascularization by Neurovascular Team decision.

carotid revascularization
transient ischemic attack
angiography
nascet method
stroke
  • 0 views
  • 19 Feb, 2024
A Study Evaluating The Safety Efficacy and Pharmacokinetics Of Ipatasertib In Combination With Atezolizumab And Docetaxel In Metastatic Castration-Resistant Prostate Cancer (mCRPC).

The study consists of two parts: [1] Part A: Safety run-in cohort of approximately 12 participants; [2] Part B: Expansion cohort of approximately 38 participants. All participants in this study will continue to be treated until progression of disease, loss of clinical benefit, unacceptable toxicity or withdrawal of consent.

prostate cancer
adenopathy
bone scan
bone lesion
adenocarcinoma
  • 0 views
  • 19 Feb, 2024
Early Screening of Autism Spectrum Disorder in General and Pediatric Practices

The second line professionals are note always trained to use diagnostic tools and tend to address all the children to the third line, even when the diagnostic is not complex. The third lign is saturated by all these requests.

neurodevelopmental disorder
pediatric
csbs
autism
pervasive developmental disorder
  • 0 views
  • 19 Feb, 2024
Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis (FREVIVA)

People diagnosed with nrSPMS are eligible for enrollment as long as they meet all the inclusion criteria and none of the exclusion criteria. Study details include: This event-driven study will have variable duration ranging from approximately 27 to 51 months.

  • 0 views
  • 07 Aug, 2024
Supramarginal Resection in Glioblastoma

The idea that some patients are amendable to radical surgery, while others should be treated more conservatively, is not controversial in other fields of oncology. The current concept in all patients with glioblastoma is "maximum safe resection of the contrast enhancing tumor", but this may in selected cases be extended …

temozolomide
malignant brain tumor
glioma
astrocytoma
supratentorial glioblastoma multiforme
  • 0 views
  • 19 Feb, 2024
Tomosynthesis as Primary Test for Breast Cancer Screening

Randomized trial comparing tomosynthesis plus synthetic 2D Mammography vs Digital Mammography in respect to incidence of advanced cancers (interval and following round) and interval cancers.

digital mammography
cancer screening
breast cancer screening
tomosynthesis
  • 0 views
  • 19 Feb, 2024