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Found 4 clinical trials
Safety and Anti-coronavirus Response of Suppression of Host Nucleotide Synthesis in Patients With COVID-19

This will be a phase 1a randomized, open label, multi-center study with approximately 24 subjects. All subjects will receive standard of care (SOC) per institutional guidelines for treatment of hospitalized patients with COVID-19 infection. In addition to SOC, the brequinar group will receive 5 daily doses of brequinar 100 mg.

myalgia
headache
acute respiratory syndrome (sars)
PCR test
sore throat
  • 0 views
  • 19 Feb, 2024
Immunological Aspect of Thrombotic Thrombocytopenic Purpura (TTP) (Lympho-PTT)

The general objective of the proposed project is to characterise phenotypically and functionally ADAMTS13-specific memory B lymphocytes and autoreactive T lymphocytes, in particular follicular helper T lymphocytes, in the acute phase of the disease, but also during its progression after treatment. The aim is to highlight their contribution to the …

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  • 18 May, 2025
Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Localized Renal Tumor

This feasibility study will evaluate how well hyperpolarized 13C pyruvate magnetic resonance imaging (MRI) scan works in predicting tumor aggressiveness in patients with localized renal tumor. Hyperpolarized 13C pyruvate is a non-radioactive substance with potential usage in the diagnostic imaging of tumors. Hyperpolarized 13C pyruvate MRI may help doctors determine …

nephrectomy
abdominal mri
cancer
MRI
renal neoplasm
  • 0 views
  • 19 Feb, 2024
The Effectiveness of Surgical Treatment of Patients With Ischemic Cardiomyopathy

The study focuses on the development of a new personalized approach to diagnostics and surgical treatment of patients with ischemic cardiomyopathy. The algorithm for selection of patients for certain type of cardiac surgery will be developed. The models for prediction of the risks and outcomes of cardiac surgery will be …

heart surgery
bypass graft
cabg
coronary artery bypass graft
myocardial infarction
  • 0 views
  • 19 Feb, 2024