irinotecan Clinical Research Trials

Found 5 clinical trials

Featured trial

We call this “infoimagery”. It is unique to every trial and is generated based on a trials specific data eg. therapeutic area, study type, phase etc. and the centerwatch system associates the information to a matching set of related symbols and icons.

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Phase 1
Recruiting in 10s
Interventional Study
all
Endocrinology
Recruiting

Switch Maintenance in Pancreatic

This study is being done to test the safety and effectiveness of combining domvanalimab (AB154), zimberelimab (AB122), and APX005M with pancreatic cancer that has spread to other parts of body.This research study involves immunotherapy. Immunotherapy triggers the body's immune system to fight cancer cells.The names of the study drugs involved …

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24 Nov, 2025
1 location

Phase 2
For Seniors
For adults
Recruiting in 100s
Interventional Study
all
Family Medicine
Recruiting

FOLFIRINOX vs FLOT Chemotherapy for Resectable Gastric or Esophagogastric Junction Adenocarcinoma

One half of the patients gets 5-Fluorouracil (5-FU), Leucovorin, Oxaliplatin and Docetaxel (FLOT), the others 5-Fluorouracil (5-FU), Leucovorin, Oxaliplatin and Irinotecan (FOLFIRINOX). Main objective of the study is median overall survival.

docetaxel

HIV Infection

combinations

folfirinox

flot

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19 Feb, 2024
1 location

Phase 2
For Seniors
For adults
Recruiting in 100s
Interventional Study
all
Recruiting

FOLFOX6 Versus mFOLFIRINOX as First Line Chemotherapy in Metastatic Gastric Cancer or Esophagogastric Junction Adenocarcinoma (Type II-III)

One half of the patients gets 5-Fluorouracil (5-FU), Leucovorin, Oxaliplatin (FOLFOX6), the others 5-Fluorouracil (5-FU), Leucovorin, Oxaliplatin and Irinotecan (mFOLFIRINOX). Main objective of the study is progression free survival.

cancer

modified folfirinox

metastatic gastric cancer

HIV Infection

combinations

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19 Feb, 2024
1 location

Phase 1
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Family Medicine
Recruiting

Bioequivalence and the Tolerability and Antitumor Activity of Selinexor Combination Treatment

This is a Phase 1, two-part, two-arm, open-label study in patients with NSCLC who have had 1 or 2 prior lines of treatment, with 1 line containing a CPI, or patients with CRC who have had 2 prior lines of treatment (oxaliplatin- and irinotecan-based) and no prior immunotherapy. The study …

solid tumour

drug test

moderate hepatic impairment

metastatic solid tumor

adjuvant

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19 Feb, 2024
3 locations

Phase 2
For Seniors
For adults
Recruiting in 100s
Interventional Study
all
Cardiovascular Diseases
Recruiting

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative breast cancer (TNBC) that has spread, or metastasized, to other parts the body and is PD-L1-negative. The names of the study interventions involved in this study are: Sacituzumab govitecan (IMMU-132) Pembrolizumab (Keytruda; MK-3475)

corticosteroids

triple-negative breast cancer

anticoagulant therapy

cns disease

copper