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Found 8 clinical trials
The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 in Children With Henoch-sch nlein Purpura

The study aims to explore the therapeutic value and mechanism of Interleukin-2 on children with Henoch-schnlein purpura.

interleukin
aldesleukin
interleukin 2
  • 0 views
  • 19 Feb, 2024
Clinical Trial to Evaluate the Efficacy and Safety of an Immunomodulatory Therapy for the Treatment of Patients With Moderate to Severe COVID-19 Infection

An Open-label, prospective, randomized, comparative, multiple doses applied in addition to the standard of care treatment of patients with moderate to severe COVID-19 infection

cough
pneumonia
fever
covid-19
dyspnea
  • 0 views
  • 19 Feb, 2024
InterLeukin-7 (CYT107) to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection UK Cohort

Comparison of the effects of CYT107 vs Placebo administered IM at 10g/kg twice a week for two weeks on immune reconstitution of lymphopenic COVID-19 patients.

interleukins
invasive positive pressure ventilation
respiratory failure
intermittent positive pressure ventilation
covid-19
  • 0 views
  • 19 Feb, 2024
InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection FR BL Cohort

Comparison of the effects of CYT107 vs Placebo administered IM at 10g/ kg twice a week for two weeks on immune reconstitution of lymphopenic COVID-19 patients.

intermittent positive pressure ventilation
interleukins
invasive positive pressure ventilation
corticosteroids
respiratory failure
  • 0 views
  • 19 Feb, 2024
Connexin Genotypes in Cystic Fibrosis

Background: There is wide variety in lung disease phenotype for the delta F508 (homozygous) genotype. A leukocyte driven inflammation is most important for the pathogenesis of pulmonary disease in CF. Blood cytokines correlate negatively with pulmonary function in delta F508 homozygous patients. Gap junction proteins might be of importance for …

pulmonary function test
diabetes
cytokines
forced expiratory volume
cystic fibrosis
  • 0 views
  • 19 Feb, 2024
Biomarkers in Rheumatoid Arthritis Treated With Anti-interleukin-6 Therapy

The use of anti-interleukin (IL)-6 therapy, including tocilizumab, in rheumatoid arthritis or giant cell arteritis, led to the improvement or even control of disease in some patients for whom no further therapeutic options were available.

interleukin
tocilizumab
inflammatory disorder
arthritis
steroidal anti-inflammatory drugs
  • 0 views
  • 19 Feb, 2024
Aflibercept or Bevacizumab as Second-line Treatment of RAS Mutated Metastatic Colorectal Cancer

Furthermore, the serum levels of angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2), vascular endothelial growth factor-A and C (VEGF-A and C), stromal cell-derived factor-1 (SDF-1), platelet-derived growth factor beta (PDGF-), basic fibroblast growth factor (bFGF), interleukin-8 (IL-8), chemokine (C-C motif) ligand 2 (CCL2), and chemokine (C-C motif) ligand 5 (CCL5) and Placental Growth …

metastatic colorectal cancer
angiogenesis inhibitors
growth factor
vegf
aflibercept
  • 0 views
  • 19 Feb, 2024
Clinical Outcome of Anti-IL6 vs Anti-IL6 Corticosteroid Combination in Patients With SARS-CoV-2 Cytokine Release Syndrome

Therefore, early identification, treatment and prevention of the cytokine storms are of crucial importance for the patients. Immuomedulator such as interleukin-6 (IL-6) antagonist, emerged as an alternative treatment for COVID-19 patients with a risk of cytokine storms recently. In this study, we aimed to evaluate the safety and efficacy of …

interleukin-6
cytokines
shock
acute respiratory syndrome (sars)
cytokine storm
  • 0 views
  • 19 Feb, 2024