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Found 4 clinical trials
First-in-Human Dose Escalation Trial of ATRC-101 in Adults With Advanced Solid Malignancies

ATRC-101-A01 is a first-in-human, Phase 1b, open-label trial to characterize the safety, tolerability, pharmacokinetics (PK), and biological activity of escalating doses of ATRC-101, an engineered, fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a naturally-occurring human antibody.

cancer treatment
measurable disease
cancer of the ovary
growth factor
ovarian cancer
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  • 19 Feb, 2024
IVIG With Rituximab vs Rituximab as First Line Treatment of Pemphigus

Pemphigus is a rare acquired autoimmune disease in which immunoglobulin G (IgG) antibodies target desmosomal proteins to produce intraepithelial, and mucocutaneous blisters. It is potentially fatal and the average mortality of pemphigus vulgaris (PV) was 75% before the introduction of corticosteroids in the early 1950s.

enzyme-linked immunosorbent assay
rituximab
immunoglobulins
immunoglobulin
igiv
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  • 19 Feb, 2024
Validation of an Immunochromatographic Assay for IgG/IgM Antibodies to 2019- nCoV

The 2019-nCoV IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma) is a qualitative, membrane-based immunoassay for the detection of immunoglobulin G (IgG) and Immunoglobulin M (IgM) antibodies to SARS-CoV-2 in whole blood, serum or plasma specimen. Clinical specimens from patients who were suspected of being infected with 2019-nCoV will be used to …

myalgia
cough
immunoglobulins
fever
respiratory distress
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  • 19 Feb, 2024
GFAP Auto-immunity : a French Cohort Study

Glial fibrillary acidic protein (GFAP)-Immunoglobulin G (IgG) have recently been described as a biomarker of a novel inflammatory central nervous system (CNS) disorder, termed autoimmune GFAP astrocytopathy.

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  • 19 Feb, 2024