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Found 7 clinical trials
Imaging of Tumour Microenvironment in Patients With Oropharyngeal Head and Neck Squamous Cell Carcinoma Using RGD PET/CT Imaging

Known risk factors inducing squamous cell carcinomas of the head and neck are tabacco and alcohol intake. However, the incidence of human papillomavirus (HPV) related oropharyngeal carcinomas is increasing. It is known that HPV+ and HPV- tumors have a different reaction to (chemo)radiotherapy.

chemoradiotherapy
squamous cell carcinoma of the head and neck
immunohistochemistry
ct scan
carcinoma
  • 0 views
  • 19 Feb, 2024
Optimising Radiation Therapy in Head and Neck Cancers Using Functional Image-Guided Radiotherapy and Novel Biomarkers

Cohort 1: HPV-associated OPC consisting of 25 participants Cohort 2: HPV-negative OPC consisting of a minimum of 10 patients and a maximum of 53 participants Cohort 3: Base of Skull HNC consisting of 25 participants

metastasis
chemoradiotherapy
neck cancer
platinum-based chemotherapy
chemo-radiotherapy
  • 0 views
  • 19 Feb, 2024
The Agreement of hrHPV Detections Between Vaginal Self-sampling and Physician Sampling

Hygeia Touch Inc. has developed a safe and comfortable vaginal self-sampling device "Hygeia Touch Self Sampling Kit for Women" to self-collect the vaginal samples for high-risk Human Papillomavirus (hrHPV) detection. This clinical trial aimed to evaluate the agreement of hrHPV detections between vaginal self-sampling using "Hygeia Touch Self Sampling Kit …

cervical intraepithelial neoplasia
cervical disease
intraepithelial neoplasia
carcinoma
carcinoma in situ of cervix
  • 0 views
  • 19 Feb, 2024
Evaluate the Efficacy Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

This study is designed to evaluate the vaccine efficacy, immunogenicity and safety of the 9-valent Human Papillomavirus (Types 6, 11, 16, 18,31,33,45,52 and 58) Recombinant Vaccine (Hansenula Polymorpha) in Chinese Female Subjects Aged 20-45 Years .

flushed skin
recombinant vaccine
emergency contraception
cervical cancer
cancer
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  • 19 Feb, 2024
Primary Organoid Models and Combined Nucleic Acids Therapeutics for Anti-HPV Treatments

Human papilloma virus (HPV) is responsible of the most common sexually transmitted infection. It can cause severe cancer lesions, of the cervix, vulva, vagina, penis and oropharynx.

vaginal biopsy
papilloma
cervical cancer
sexually transmitted infection
PAP test
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  • 19 Feb, 2024
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.

The objective of this trial is to study the efficacy of treatment of human papilloma virus (HPV) related oropharyngeal cancer with chemotherapy followed by Transoral Robotic Surgery (TORS) as definitive treatment.

primary tumor
papilloma
chemo-radiotherapy
carcinoma
docetaxel
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  • 19 Feb, 2024
Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

This is a Phase II treatment, non-randomized, open label clinical trial to study the efficacy of the Cetuximab when administered as single agent in recurrent/ metastatic head and neck squamous cell carcinoma after the failure or intolerance of immuno-oncology or immuno-oncology combined with chemotherapy.

measurable disease
metastatic head and neck squamous cell carcinoma
cetuximab
cancer
pd-1 inhibitor
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  • 19 Feb, 2024