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Found 3 clinical trials
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  • 19 Feb, 2024
  • 1 location
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  • 19 Feb, 2024
  • 1 location
Tofacitinib for Immune Skin Conditions in Down Syndrome

People with Down syndrome (DS) display widespread immune dysregulation, including several immune skin conditions. This study hypothesizes that pharmacological inhibition of the increased interferon (IFN) signaling seen in DS is safe and could improve associated skin conditions. The study evaluates the safety and efficacy treatment with Tofacitinib, an FDA-approved drug …

atopy
psoriasis
skin disorder
dermatitis
down syndrome
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  • 19 Feb, 2024