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Found 1 clinical trials

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Phase 2
For Seniors
For adults
Recruiting in 10s
Interventional Study
For Females
Cardiovascular Diseases
Recruiting

Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer

Glucose starvation and metformin have synergistic antitumor effects that are mediated through the concomitant inhibition of glycolysis and mitochondrial oxidative phosphorylation. The BREAKFAST trial will evaluate the antitumor activity of combining cyclic fasting-mimicking diet (FMD), which reproduces the in vitro effects of glucose starvation, plus/minus metformin with standard preperative anthracycline-taxane …

potassium

preoperative chemotherapy

oophorectomy

breast cancer

progesterone receptor

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19 Feb, 2024

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