etoposide Clinical Research Trials

Found 5 clinical trials

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Multi-country trial
Phase 3
For Seniors
For adults
Recruiting in 100s
Interventional Study
all
Family Medicine
Recruiting

A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung Cancer

This study will evaluate the efficacy of tiragolumab plus atezolizumab and carboplatin and etoposide (CE) compared with placebo plus atezolizumab and CE in participants with chemotherapy-naive extensive-stage small cell lung cancer (ES-SCLC).

extensive stage small cell lung cancer

tiragolumab

carboplatin

etoposide

solid tumour

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19 Feb, 2024

Multi-country trial
Phase 1
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Family Medicine
Recruiting

A Study Evaluating The Safety Tolerability Pharmacokinetics And Efficacy Of Venetoclax In Combination With Atezolizumab Carboplatin And Etoposide In Participants With Untreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC).

A study consisting of a dose-escalation phase and a dose-expansion phase to evaluate the safety, tolerability, pharmacokinetics, and efficacy of venetoclax in combination with atezolizumab, carboplatin, and etoposide.

venetoclax

extensive stage small cell lung cancer

colony stimulating factor

serum pregnancy test

chemoradiotherapy

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19 Feb, 2024

Phase 3
For pediatric ages
For adults
Recruiting in 1000s
Interventional Study
all
Hematology
Recruiting

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

This phase III trial compares standard chemotherapy to therapy with CPX-351 and/or gilteritinib for patients with newly diagnosed acute myeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop the growth of cancer cells, either by …

chemotherapy drug

methotrexate

gemtuzumab ozogamicin

blood count

mental retardation

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2 annotations
19 Feb, 2024

Phase 2
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Recruiting

Patients With ES-SCLC and ECOG PS=2 Receiving Atezolizumab-Carboplatin-Etoposide

Compared with non-small-cell lung cancer (NSCLC) SCLC has a unique natural history with a shorter doubling time, higher growth fraction, earlier development of widespread metastases, and uniform initial response to chemo- or radiotherapy. The combination of cis- or carboplatin and etoposide is the standard of care in the first-line treatment …

systemic therapy

ipilimumab

pd-l1

small cell lung cancer

tuberculosis

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19 Feb, 2024

Phase 2
For pediatric ages
For Seniors
Recruiting in 100s
Interventional Study
all
Recruiting

Pegaspargase-COEP Chemotherapy Combined With Radiotherapy for Extra-nodal NK/T Cell Lymphoma

This phase II study aimed to evaluate the efficacy and safety of pegaspargase, cyclophosphamide, vincristine, etoposide and prednisone (COEPL) regimen combined with radiotherapy for patients with newly diagnosed ENKTL.