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Found 14 clinical trials
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Neoadjuvant Chemoradiotherapy Combined With Perioperative Toripalimab in Locally Advanced Esophageal Cancer

However, the efficacy and safety of immunotherapy therapy in surgery-based multidisciplinary treatment of local advanced esophageal cancer still need a lot of clinical studies to further confirm. The aim of this study was to evaluate the efficacy and safety of the neoadjuvant chemoradiotherapy combined with perioperative toripalimab in patients with …

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  • 19 Feb, 2024
  • 1 location
Aspirin Use for Gastric Cancer Prevention in the Early Gastric Cancer Patients

This study aimed to investigate the effect of low-dose (100 mg) asprin on the prevention of gastric cancer in the early gastric cancer patients with negative H. pylori status who underwent endoscopic submucosal dissection.

endoscopic submucosal dissection
cancer treatment
cancer
aspirin
prevention of gastric cancer
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  • 19 Feb, 2024
  • 9 locations
A Comparison Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy

The MIE with intrathoracic anastomosis (Ivor-Lewis) is increasingly used for the treatment of mid and lower esophageal cancers. Our study is trying to compare the safety, feasibility, and short-term and long- term outcomes between MIE Ivor-Lewis approach and MIE McKeown approach for the treatment of lower thoracic esophageal cancer and …

esophagus cancer
thoracic surgery
esophagectomy
cancer
esophageal cancer
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  • 19 Feb, 2024
  • 1 location
Study of Camrelizumab (SHR-1210) in Combination With Concurrent Chemoradiotherapy in Locally Advanced Esophageal Cancer

This is a randomised, double-blinded, placebo-controlled, multi-center phase III trial, comparing the efficacy and safety of treatment with Camrelizumab (SHR-1210) + definitive chemoradiotherapy(dCRT) vs placebo+dCRT for locally advanced esophageal cancer patients in China. Camrelizumab (SHR-1210) is a humanized anti-PD1 IgG4 monoclonal antibody.

squamous cell carcinoma of esophagus
monoclonal antibody therapy
paclitaxel
shr-1210
cisplatin
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  • 19 Feb, 2024
  • 1 location
Concurrent Chemoradiotherapy After Endoscopic Resection for Stage I Esophageal Carcinoma

This is a prospective single-arm study of endoscopic resection (ER) following concurrent chemoradiotherapy for stage I esophageal squamous cell carcinoma, to find if the treatment combination is useful by assessing its safety and efficacy.

bone metastases
primary lesion
lymph node metastases
esophageal squamous cell carcinoma
blood pregnancy test
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  • 19 Feb, 2024
  • 1 location
Pembrolizumab Plus Paclitaxel Cisplatin Followed by Surgery for Locally Advanced ESCC

The purpose of this study is to observe and evaluate the efficacy and safety of pembrolizumab plus paclitaxel, cisplatin followed by Da Vinci robot radical surgery for locally advanced esophageal squamous cell carcinoma.

squamous cell carcinoma of esophagus
pembrolizumab injection
cisplatin
serum pregnancy test
paclitaxel
  • 0 views
  • 19 Feb, 2024
  • 1 location