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Found 9 clinical trials
Modality of Adjuvant Radiotherapy and Chemotherapy for Stage Endometrial Cancer

There is a consensus that adjuvant radiochemotherapy is needed for stage endometrial cancer, but the best modality of radiochemotherapy is still uncertain. The retrospective data of our center showed that the sequential radiochemotherapy of "chemotherapy-radiotherapy-chemotherapy" in the "sanwich" mode could improve the survival outcome in patients with advanced endometrial cancer.

adenocarcinoma
stage iii endometrial cancer
neutrophil count
hysterectomy
endometrial adenocarcinoma
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  • 19 Feb, 2024
Sentinel Lymph Node Sampling for Patients With Middle-high Risk Endometrial Cancer Confined to the Uterus

Aim To investigate the effect of sentinel lymph node (SLN) sampling on the prognosis of patients with middle-high risk endometrial cancer obviously confined to the uterus before surgery.

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  • 19 Feb, 2024
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

carboplatin paclitaxel
measurable disease
olaparib
maintenance therapy
recurrent endometrial cancer
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  • 19 Feb, 2024
A Study of Sacituzumab Govitecan (IMMU-132) in Endometrial Carcinoma

This is a non-randomized Phase 2 study of sacituzumab govitecan (IMMU-132) in subjects with persistent or recurrent endometrial carcinoma.

formalin-fixed paraffin-embedded
measurable disease
metastasis
major surgery
hair thinning
  • 0 views
  • 19 Feb, 2024
De-escalated Conformal Radiation Expedited Sequentially With Chemotherapy for Endometrial Cancer

The goal of this study is to evaluate short course radiation in the post-operative female pelvis after hysterectomy in stage III-IVA endometrial adenocarcinoma patients, or any stage patients with uterine serous or carcinosarcoma histology. The investigators hypothesize that short course pelvic radiation will have an acute and late grade 3-4 …

adenocarcinoma
neutrophil count
carcinosarcoma
hysterectomy
endometrial adenocarcinoma
  • 0 views
  • 19 Feb, 2024
The Application of Real-Time Near-infrared Imaging in Gynecological Surgery

Removing in situ and metastasis lesions completely during gynecological surgery is central to reduce the recurrence and death, and the identification of lesions in traditional gynecological surgery often depends on the experience of surgeons. The identification of nerves is often needed in gynecological surgery, such as the obturator nerves in …

metastasis
hysterectomy
cervical cancer
infrared imaging
endometriosis
  • 0 views
  • 19 Feb, 2024
Endometrial Cancer Conservative Treatment (E.C.Co). A Multicentre Archive

Approximately one fourth of cases of endometrial cancer (EC) are diagnosed in premenopausal women, of whom approximately 40% wish to preserve their fertility. When arising in young women, EC usually presents with favorable prognostic features, as a focal, well differentiated endometrioid tumor, with minimal or absent myometrial invasion.

progesterone receptor
hysterectomy
estrogen
infertility
progesterone
  • 0 views
  • 19 Feb, 2024
Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease

This study is being done to find out how often endometrial cancer recurs after the standard treatment as well as how often the standard treatment results in a lymphedema.

adenocarcinoma
melanoma
positron emission tomography
lymphedema
metastasis
  • 0 views
  • 19 Feb, 2024
The Role of Micrometastasis and Isolated Tumor Cells (ITCs) in Endometrial and Cervical Cancer. A Multicenter Study.

The role of small-volume lymph node disease (ITC and micro metastases) among patients with endometrial or cervical cancer submitted to sentinel node (SLN) procedure is not clearly defined. This study was designed to create a dataset of patients with lymph nodal disease. Data on type and volume of lymph nodal …

nucleic acid amplification
pathological evaluation
metastasis
sentinel node
tumor cells
  • 0 views
  • 19 Feb, 2024