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Found 21 clinical trials
Study in Subjects With Relapsed/Refractory Follicular Lymphoma

This is a multicenter, double-blind, active-controlled, randomized, 3-stage, biomarker enrichment design featuring early futility stopping and sample-size re-estimation with safety run-in designed to evaluate the efficacy and safety of tazemetostat in combination with R2 in subjects with R/R FL, who have completed at least 1 prior systemic chemotherapy, immunotherapy, or …

cytotoxic chemotherapy
hepatitis
chemoimmunotherapy
systemic therapy
bilateral oophorectomy
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  • 19 Feb, 2024
Predictors of Intestinal Anastomosis Leakage Application of New Predictors and New Scores

Aim of the work This study aims at; Early detection of disruption and leakage of intestinal anastomotic sites whether small or large intestine by using biochemical markers as predictors and indicators of leakage with application of scoring scale to assess presence or absence of leakage.

early detection
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  • 19 Feb, 2024
Combining Biomarkers (AFP AFP-L3 and PIVKA-II) and Image Tools for Early Detection of Hepatocellular Carcinoma

In this study, three biomarkers tests (AFP, AFP-L3 and PIVKA-II) and abdominal sonography or CT scans are performed every 6 months to detect hepatocellular carcinoma (HCC) early in patients with cirrhosis, a high-risk group of HCC. The aim of this study is to confirm the early HCC diagnosis rate in …

gastric varices
hypoalbuminemia
ct scan
fibrosis
encephalopathy
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  • 19 Feb, 2024
Diffusion Basis Spectrum Imaging of the Prostate

Diffusion Basis Spectrum Imaging (DBSI) represents a potential leap forward in improving prostate cancer early detection: a non-invasive and accurate imaging test for clinically significant prostate cancer.

biopsy of prostate
prostate cancer screening
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  • 19 Feb, 2024
The PREDICT Study: Prospective Early Detection In a Population at High-risk for Common Malignant Tumor

This is a observational, multicenter study, monitoring the circulating tumor DNA (ctDNA) in people who is at risk of cancersassessing the sensitivity and specificity of ctDNA detection in early screening of pan-carcinoma.

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  • 19 Feb, 2024
Cohort Study of Pancreatic Cancer Risk

This study is designed to develop a cohort of individuals without pancreatic cancer, but who are at increased risk of developing it due to family history or genetic predisposition. These high-risk individuals will be asked to provide baseline and annual (serial) follow-up blood samples for the duration of the study …

  • 0 views
  • 19 Feb, 2024
ImmuneRACE - Immune Response Action to COVID-19 Events

ImmuneRACE is a study, which is designed to better understand the immune response to COVID-19. This is critically important because the immune system may be able to tell us important information about how our own bodies detect and respond to the disease that current tests cannot. De-identified data collected from …

oropharyngeal
coronavirus infection
  • 0 views
  • 19 Feb, 2024
EAS Familial Hypercholesterolaemia Studies Collaboration

Familial hypercholesterolaemia (FH) is a common genetic disorder resulting in marked elevations in low-density lipoprotein cholesterol (LDL-C). If untreated, lifelong exposure to elevated LDL-C results in a substantially increased risk of (premature) cardiovascular disease as compared to the general population. Although FH adverse cardiovascular outcomes are potentially preventable through early …

hypercholesterolemia
premature
lipoprotein cholesterol
early detection
early identification
  • 0 views
  • 19 Feb, 2024
Prostate Screening for Men With Inherited Risk of Developing Aggressive Prostate Cancer PATROL Study

Studying samples of blood, urine, and/or tissue in the laboratory may help doctors further understand the genetics of prostate cancer and help identify ways to detect cancer earlier, thereby improving treatment and methods of early detection in the future.

prostate carcinoma
PMS2
digital rectal exam
ATM
carcinoma
  • 0 views
  • 19 Feb, 2024
Quantifying Digital Behavior on Smart Phones - Data From Stroke Survivors

In this study, we want to continuously record the interaction of 50 stroke survivors with their smartphones during the first 3 months after discharge. The linkage of smart phone use to function and quality of life will be assessed with standardized outcome measures at defined time points.

recurrent strokes
  • 0 views
  • 19 Feb, 2024