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Found 17 clinical trials
Probe-based Confocal Laser Endomicroscopy in Critically Ill COVID-19 Patients

The study is devoted to the comparative analysis of the data received in patients with COVID-19 lung pathology using the method of probe-based confocal laser endomicroscopy of distal airways and two reference methods: high resolution computed tomography and morphology (in some patients).

ct scan
critically ill
chronic obstructive pulmonary disease
critical illness
lung disease
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  • 19 Feb, 2024
Navigation Endoscopy to Reach Indeterminate Lung Nodules Versus Trans-Thoracic Needle Aspiration

Two different procedures are available for lung nodule biopsy: a computed tomography guided biopsy ("CT-guided biopsy") which consists of sampling the nodule from the "outside-in", through the chest wall with CT guidance, and navigation bronchoscopy, which is a procedure using technology designed to guide a catheter through the natural airway …

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  • 19 Feb, 2024
Descriptive and Evaluation Study of the Use of Pulmonary Ultrasound in the Initial Management of Pregnant Women in the Context of COVID-19

Objectives : Primary objective: To describe the lung ultrasound lesions in pregnant women in case of suspected or confirmed COVID-19 Secondary objectives: To compare the lung ultrasound lesions with chest Computed Tomography -scanner (CT-Scan) lesions To evaluate the performances of the lung ultrasound to diagnose COVID-19 in pregnant women To …

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  • 19 Feb, 2024
Unilateral Versus Bilateral Pedicle Screw Fixation for Lumbar Degenerative Diseases

Determining the treatment strategy for patients with degenerative diseases of the spine is extremely difficult, without an accurate understanding of the nature of stress distribution in the vertebral-motor segments of the spine, as well as biomechanical changes that are associated with degenerative diseases of the spine. In this clinical study, …

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  • 19 Feb, 2024
Efficacy and Safety of SP-8203 in Patients With Ischemic Stroke Requiring rtPA

This clinical trial is designed to evaluate the efficacy and safety of the combination therapy of SP-8203 (Otaplimastat) and recombinant tissue Plasminogen Activator (rtPA) standard of care. In this clinical trial, rtPA will be injected intravenously using an infusion device. If reperfusion is not occur in spite of rtPA therapy, …

brain mri
stroke
deficit
plasminogen activator
flair
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  • 19 Feb, 2024
18F-DCFPyL PET/CT Impact on Treatment Strategies for Patients With Prostate Cancer

The main purpose of this phase II trial study is to determine whether a positron emission tomography (PET)/computed tomography (CT) scan using 18F-DCFPyL affects the clinical management plan in Veterans. In this study, the management plan prior to and after 18F-DCFPyL PET/CT will be recorded by specific questionnaires and corresponding …

prostatectomy
external beam radiation therapy
conventional imaging
ct scan
salvage therapy
  • 0 views
  • 19 Feb, 2024
Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

They will have an electroencephalogram to record brain activity. They will have a computed tomography (CT) scan or magnetic resonance imaging (MRI). A CT is a series of X-rays of the body. An MRI uses magnets and radio waves to take pictures of the body.

electroencephalogram
renal function
blood transfusion
pediatric
blood tests
  • 0 views
  • 19 Feb, 2024
Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication

Prospective, multi-center, non-randomized study with consecutive, eligible subject enrollment at each site, for the evaluation of the ChEVAS System for Endovascular Repair of Complex Abdominal Aortic Aneurysms.

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  • 19 Feb, 2024
Concurrent Chemoradiation and Durvalumab for Locoregionally Advanced Nasopharyngeal Carcinoma

The investigators propose a phase II randomized-controlled study on using durvalumab in combination with induction chemotherapy followed by concurrent chemoradiation and adjuvant durvalumab, compared to induction chemotherapy followed by concurrent chemoradiation for previously untreated locoregionally advanced stage III to IVA NPC. In parallel, the investigators will also perform collateral tumor …

follicle stimulating hormone
ffpe
intra-articular injection
oophorectomy
irreversible toxicity
  • 0 views
  • 19 Feb, 2024
Bioequivalence and the Tolerability and Antitumor Activity of Selinexor Combination Treatment

This is a Phase 1, two-part, two-arm, open-label study in patients with NSCLC who have had 1 or 2 prior lines of treatment, with 1 line containing a CPI, or patients with CRC who have had 2 prior lines of treatment (oxaliplatin- and irinotecan-based) and no prior immunotherapy. The study …

colorectal cancer
metastatic nsclc
non-small cell lung cancer
programmed cell death protein 1
leucovorin
  • 0 views
  • 19 Feb, 2024