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Found 38 clinical trials
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

Accepts healthy volunteers
mental state examination
apolipoprotein e4
mini-mental state examination
alzheimer's disease
  • 32 views
  • 20 Sep, 2024
  • 127 locations
A Clinical Trail of Traditional Chinese Medicine Rehabilitation for Stroke Lead to Dysphagia / Cognitive Disorder

The traditional Chinese medicine rehabilitation for the deglutition and cognitive impairment after stroke will be intervened, which can promote the recovery of dysphagia and cognitive function of stroke patients, reduce the disability rate and improve the quality of life.

dysphagia
acupuncture
cerebral infarction
infarct
ischemic stroke
  • 0 views
  • 19 Feb, 2024
Determinants of Neonatal Anemia in Women Carrying Multiples

Moreover, the developing brain is increasingly recognized to be susceptible to Fe insufficiency in utero and growing data support that suboptimal Fe stores at birth are associated with long-term irreversible cognitive deficits in the offspring. To address these gaps in knowledge the investigators will monitor weight gain, hematological measures, Fe …

Accepts healthy volunteers
  • 0 views
  • 23 Dec, 2024
  • 2 locations
Effect of Preoperative Intervention With Folic Acid and Vitamin B12 on Postoperative Neurobehavioral Changes in Children

Comparison of preoperative folic acid and VitB12 intervention on postoperative delirium and long-term neurobehavioral changes in children under general anesthesia

delirium
vitamin b12 level
anesthesia
postoperative delirium
  • 0 views
  • 19 Feb, 2024
Application of LLM Care and Related Affective Computing Systems on People With Parkinson's Disease

The study is an adaptation of the Long Lasting Memories (LLM) (NCT02267499) and the subsequent LLM Care (NCT02313935) projects in patients with Parkinson's Disease (PD). The study aims to examine the viability and any potential benefits of cognitive and physical training, as offered via the ICT-based (non-pharmacological) intervention of LLM …

diabetes
chronic disease
dyskinesia
parkinson's disease
neurodegeneration
  • 0 views
  • 19 Feb, 2024
A Randomised Control Trial Comparing Functional Outcomes for Navigated Kinematically Aligned TKR Versus Navigated Mechanically Aligned TKR

The overall aim of the study is to compare navigated kinematically aligned total knee replacements (KA TKR) with navigated mechanically aligned TKR (MA TKR) in terms of function and ROM The objectives are therefore: To compare the functional outcomes of KA TKR versus MA TKR performed using navigation technique To …

  • 0 views
  • 19 Feb, 2024
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

Cardiac surgery appears to carry the highest risk of postoperative cognitive dysfunction (POCD). These cognitive deficits are associated with increased mortality, prolonged hospital stay and loss of independence.

postoperative cognitive dysfunction
coronary artery bypass graft
memory impairment
comatose
dexmedetomidine
  • 0 views
  • 19 Feb, 2024
Tai Chi Chuan as Rehabilitation Program for Mild Cognitive Impairment in Type 2 Diabetes Mellitus Patients

The patients with type 2 diabetes mellitus (T2DM) is expected to rise to 439 million in 2030, accounting for 7.7% the population in the world. There are nearly 10 million T2DM patients with mild cognitive impairment (MCI) among people over 65 years old , accounting for about 8% of the …

diabetes
mild cognitive impairment
cognitive impairment
rehabilitation therapy
demented
  • 0 views
  • 19 Feb, 2024
Cognitive Training and Brain Stimulation in Prodromal Alzheimer's Disease

The aim of this study is to investigate whether a tDCS-accompanied intensive cognitive training of working memory leads to performance improvement in individuals with prodromal Alzheimer's disease.

cognitive training
cognitive impairment
alzheimer's disease
prodromal alzheimer's disease
mild cognitive impairment
  • 0 views
  • 19 Feb, 2024
An Advance Care Planning Programme for Persons With Early Stage Dementia or Mild Cognitive Impairment in the Community

Advance care planning (ACP) has been widely advocated for persons with early stage dementia (PWEDs) and persons with mild cognitive impairment (MCI). This proposed study attempts to promote the uptake of ACP for this population and their family caregivers in the community and to examine the effects of an ACP …

mild cognitive impairment
cognitive impairment
dementia
  • 0 views
  • 19 Feb, 2024