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Found 2 clinical trials
Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia"

This is a Phase 1-2, multicenter, international, single-arm, open-label study designed to identify a recommended dose of bosutinib administered orally once daily in pediatric patients with newly diagnosed chronic phase Ph+ CML (ND CML) and pediatric patients with Ph+CML who have received at least one prior TKI therapy (R/I CML), …

cml - philadelphia chromosome
tyrosine
immunodeficiency
molecular diagnosis
tyrosine kinase inhibitor
  • 0 views
  • 19 Feb, 2024
A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS CMML or AML

Study ASTX030-01 is designed to move efficiently from Phase 1 to Phase 3. Phase 1 consists of an open-label Dose Escalation Stage (Stage A) using multiple cohorts at escalating dose levels of oral cedazuridine and azacitidine (only one study drug will be escalated at a time) followed by a Dose …

myelodysplastic/myeloproliferative neoplasm
cedazuridine
myelodysplastic syndrome
immunosuppression
major surgery
  • 0 views
  • 19 Feb, 2024