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Found 5 clinical trials
High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)

This is an international multicenter, open-label, randomized phase III trial including three sequential randomizations to assess efficacy of induction and consolidation chemotherapies and radiotherapy for patients with high-risk neuroblastoma.

localized neuroblastoma
myocardial infarction
arrhythmia
bone marrow disease
bacterial vaccines
  • 0 views
  • 19 Feb, 2024
  • 1 location
Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer

This study is a one-arm, open, phase II clinical study, and the study subjects are locally advanced and inflammatoryPatients with sexual or early HER2-positive breast cancer entered the trial period after signing informed consentTo evaluate trastuzumab combined with pyrrolitinib and chemotherapy regimen (TCbH+Py) for HER2 positive breastPathologic complete response rate …

her2+ breast cancer
targeted therapy
platelet count
adenocarcinoma
neutrophil count
  • 0 views
  • 19 Feb, 2024
  • 1 location
Vacuum Assisted Biopsy Immediately Before Surgery as an Intra- or Pre-Operative Surrogate for Patient Response to Neoadjuvant Chemotherapy for Breast Cancer

Neoadjuvant chemotherapy (NAC) is common practice in the primary treatment of breast cancer, leading to a complete pathologic remission (pCR) of the tumor in more than 50% in aggressive tumor types. As NAC induces different response patterns, radiologic imaging is not sufficiently accurate in predicting residual disease. Because of this …

luminal
cancer surgery
residual tumor
adjuvant chemotherapy
immunostimulant
  • 0 views
  • 19 Feb, 2024
  • 16 locations
Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma

To compare the effectiveness and toxicity of nedaplatin versus cisplatin in induction chemotherapy combined with concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma.

nasopharyngeal carcinoma
liver function tests
carcinoma
karnofsky performance status
metastasis
  • 0 views
  • 19 Feb, 2024
  • 1 location
P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

An open-label, multi-center, single and cyclic ascending dose study of P-PSMA-101 autologous CAR-T cells in patients with mCRPC.

metastatic hormone refractory prostate cancer
metastasis
measurable disease
metastatic castration-resistant prostate cancer
metastatic cancer
  • 0 views
  • 19 Feb, 2024
  • 3 locations