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Found 5 clinical trials
High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)

This is an international multicenter, open-label, randomized phase III trial including three sequential randomizations to assess efficacy of induction and consolidation chemotherapies and radiotherapy for patients with high-risk neuroblastoma.

oxygen saturation
renal toxicity
pulse oximetry
heart disease
hyperhydration
  • 0 views
  • 19 Feb, 2024
  • 1 location
Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer

This study is a one-arm, open, phase II clinical study, and the study subjects are locally advanced and inflammatoryPatients with sexual or early HER2-positive breast cancer entered the trial period after signing informed consentTo evaluate trastuzumab combined with pyrrolitinib and chemotherapy regimen (TCbH+Py) for HER2 positive breastPathologic complete response rate …

neutrophil count
cancer chemotherapy
bisphosphonate therapy
invasive breast cancer
bisphosphonate
  • 0 views
  • 19 Feb, 2024
  • 1 location
Vacuum Assisted Biopsy Immediately Before Surgery as an Intra- or Pre-Operative Surrogate for Patient Response to Neoadjuvant Chemotherapy for Breast Cancer

Neoadjuvant chemotherapy (NAC) is common practice in the primary treatment of breast cancer, leading to a complete pathologic remission (pCR) of the tumor in more than 50% in aggressive tumor types. As NAC induces different response patterns, radiologic imaging is not sufficiently accurate in predicting residual disease. Because of this …

luminal b breast cancer
luminal
cancer surgery
immunomodulators
residual tumor
  • 0 views
  • 19 Feb, 2024
  • 16 locations
Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma

To compare the effectiveness and toxicity of nedaplatin versus cisplatin in induction chemotherapy combined with concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma.

chemoradiotherapy
liver function tests
nasopharyngeal carcinoma
induction chemotherapy
concurrent radiochemotherapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

An open-label, multi-center, single and cyclic ascending dose study of P-PSMA-101 autologous CAR-T cells in patients with mCRPC.

metastatic disease
castration-resistant prostate cancer
rimiducid
metastatic castration-resistant prostate cancer
cancer
  • 0 views
  • 19 Feb, 2024
  • 3 locations