central nervous system tumors Clinical Research Trials

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Found 3 clinical trials

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For pediatric ages
For adults
Recruiting in 10s
Interventional Study
all
Recruiting

Memantine for the Reduction of Cognitive Impairment After Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

This early phase I trial studies the feasibility of giving memantine for the reduction of cognitive impairment after radiation therapy in pediatric patients with central nervous system tumors. Memantine may reduce the effects of radiation therapy on memory and thinking.

effects of radiation therapy

direct bilirubin

cognitive impairment

memantine

cancer

0 views
19 Feb, 2024

Phase 2
For pediatric ages
For adults
Recruiting in 10s
Interventional Study
all
Endocrinology
Recruiting

Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

glomerular filtration rate

recurrent melanoma

lymphoma

cns tumor

melanoma

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19 Feb, 2024

Phase 1
For pediatric ages
For adults
Recruiting in 10s
Interventional Study
all
Recruiting

CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas

The blood brain barrier (BBB) prevents some drugs from successfully reaching the target source. Convection-Enhanced Delivery (CED) is a method of direct infusion of drugs under controlled pressure to the tumor that may reduce systemic side effects of drugs in the patient. The purpose of this Phase I study is …

side effects of drugs

anticonvulsants

pediatric

acute infection

diffuse intrinsic pontine glioma

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19 Feb, 2024