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Found 1 clinical trials
A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS CMML or AML

Phase 1 consists of an open-label Dose Escalation Stage (Stage A) using multiple cohorts at escalating dose levels of oral cedazuridine and azacitidine (only one study drug will be escalated at a time) followed by a Dose Expansion Stage (Stage B) of ASTX030. Phase 2 is a randomized open-label crossover …

ringed sideroblasts
immunosuppression
graft versus host disease
cytotoxic chemotherapy
major surgery
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  • 19 Feb, 2024