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Found 3 clinical trials
Personalized Second Chance Breast Conservation (PSCBC): A Two Center Prospective Phase II Clinical Study

The goal of the study is to investigate the feasibility of enabling a second chance for breast conservation in patients with in-breast recurrences after a previous lumpectomy and RT, investigators propose to test partial breast irradiation with the target volume encompassing the entire surgical bed with 1.0-1.5 cm margins.

breast irradiation
systemic therapy
lumpectomy
breast carcinoma
radiotherapy to breast
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  • 19 Feb, 2024
Clinical Database of Safe Personalized Adjuvant Breast Radiotherapy Based on Individual Radiosensitivity

Severe but also moderate toxicities after curative-intent radiotherapy (RT), such as a poor cosmetic outcome following breast cancer can have a negative impact on quality of life and a marked effect on subsequent psychological outcome. Nevertheless, current practice standards commonly prescribe radiation dose and volume without regard to individual radiosensitivity. …

breast irradiation
luminal
cancer surgery
breast cancer
immunomodulators
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  • 19 Feb, 2024
Observational Study of Intra-operative Partial Irradiation of Invasive Ductal Breast Carcinomas With a Good Prognosis

The treatment of these tumors combines breast-conserving surgery and external whole breast irradiation for 6.5 weeks. A true de-escalation of treatment is taking place with these tumors, both surgically and medically.

lymph node dissection
sentinel node
breast cancer
cancer
radiation oncology
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  • 19 Feb, 2024