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Found 11 clinical trials
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

This phase III trial compares standard chemotherapy to therapy with CPX-351 and/or gilteritinib for patients with newly diagnosed acute myeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop the growth of cancer cells, either by …

gemtuzumab
white blood cell count
daunorubicin
blast count
acute myeloid leukemia
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  • 2 annotations
  • 19 Feb, 2024
A Study to Test How Different Doses of BI 456906 Are Tolerated in Japanese Men With a Body Mass Index (BMI) Between 23 and 40 kg/m2

Main objectives are to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of different dose escalation schemes of BI 456906 in healthy Japanese male subject with BMI 23-40 kg/m2 and to determine a dose escalation scheme for future studies.

hysterectomy
tubal occlusion
oral contraceptives
oophorectomy
vasectomy
  • 0 views
  • 19 Feb, 2024
Diabetes Nutrition Education for American Indian and Alaska Native Communities

The Study Aims include: piloting the newly adapted program at 6 AI/AN collaborating sites to gain feedback on satisfaction, likability, usability and clinical outcomes such as HgA1C (measure of blood sugar control), blood pressure, and body mass index (BMI).

nutrition education
body mass index
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  • 19 Feb, 2024
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

Eligibility People ages 18-70 with mild to moderate active psoriasis not currently treated with biological therapy Design Participations will be screened with: Medical and medication history Physical exam Measure of body mass index Skin exam Blood and urine tests Participants will have visit 1. They will have repeats of the …

body mass index
vitamins
psoriasis
nicotinamide
niacin
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  • 19 Feb, 2024
The Effect of The Personalized Patient Engagement Plan on Diabetes Management

This study evaluates the effect of Personalized Patient Engagement Plan on diabetes management in patients with at least six months of Type-2 Diabetes. The research is planned to be carried out as an experimental study with pretest-posttest control groups. Half of the participants will receive the Personalized Patient Engagement Plan; …

antidiabetic agents
antidiabetic agent
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  • 19 Feb, 2024
CoV-ICU Score Intensive Care Unit SARS-CoV-2

We aim to find an answer to the question of whether the patient's CRP, ferritin, D-dimer, Oxygen Saturation, lymphocyte count, and body mass index can be used as a criterion for admitting patients with COVID to the intensive see unit.

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  • 19 Feb, 2024
Maternal Obesity and Offspring Neurodevelopment

Our goals are to characterize the effects of maternal obesity during pregnancy on infant brain development, reveal the neurodevelopmental consequences, and identify possible mechanisms causing these effects. Our overall hypothesis is that maternal obesity during pregnancy exposes the fetus to an inflammatory environment that affects infant brain structural and functional …

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  • 19 Feb, 2024
Deciphering AMD by Deep Phenotyping and Machine Learning- Prospective Study - PINNACLE

We will conduct a prospective non-interventional study including 400 early AMD patients (=600 untreated early AMD eyes, including both unilateral (AREDS IV) and bilateral (AREDS II)) over 3 years to specifically investigate the morphological sequence of events preceding the conversion towards late AMD. All patients will be followed by OCT …

geographic atrophy
atrophy
neovascularization
mydriasis
drusen
  • 0 views
  • 19 Feb, 2024
Life Style Modification Medical and Surgical Management in Patients With Obesity

In this is an observational study, obese patients that administed and followed in endocrinology clinic of Marmara University Medical school hospital will follow for clinical and laboratory parameters prospectively for 5 years

body mass index
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  • 19 Feb, 2024
The Assessment of Talar Cartilage in Patients With Unilateral Traumatic Transtibial Amputation

Increased risk of osteoarthritis (OA) has been previously demonstrated in patients with lower limb amputation. Although there are many studies on knee joint of intact limb of amputees in the literature, the number of studies on intact foot and ankle is extremely limited. The primary aim of the study is …

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  • 19 Feb, 2024