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Found 3 clinical trials
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients

To evaluate the pharmacokinetics (PK) of venglustat in Autosomal Dominant Polycystic Kidney Disease patients (Stages 1 and 2). To determine the effect of venglustat on pain and fatigue, based on patient reported diary (Stages 1 and 2).

autosomal dominant
renal function
ophthalmological examination
tolvaptan
treatment regimen
  • 0 views
  • 19 Feb, 2024
  • 81 locations
LIPAD - LRRK2 International Parkinson's Disease Study

LRRK2-associated Parkinson's syndrome is clinically indistinguishable from idiopathic Parkinson's disease. It is inherited autosomal dominant, that means if one of the two gene copies is altered, the disease occurs. However, the disease does not occur in every mutation carrier, the penetrance is reduced and the mechanisms for that are still …

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  • 19 Feb, 2024
Early Detection of Familial Hypercholesterolemia in Children

Heterozigous FH is an underdiagnosed disease in the paediatric population. Its early detection, would allow us to initiate lifestyle therapeutical changes and early pharmacological therapy if necessary. This is a key fact to reduce atherosclerosis progression and cardiovascular risk in adulthood. Moreover, it will allow, detecting the first and second …

maternal transmission
early detection
atherosclerosis
diabetes
hypercholesterolemia
  • 0 views
  • 19 Feb, 2024