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Found 2 clinical trials
Study Assessing the Efficacy and Safety of Alpelisib + Nab-paclitaxel in Subjects With Advanced TNBC Who Carry Either a PIK3CA Mutation or Have PTEN Loss Without PIK3CA Mutation

The purpose of this study is to determine whether treatment with alpelisib in combination with nab-paclitaxel is safe and effective in subjects with advanced triple negative breast cancer (aTNBC) who carry either a PIK3CA mutation (Study Part A) or have PTEN loss without PIK3CA mutation (Study Parts B1 and B2)

paclitaxel
measurable disease
metastasis
breast cancer
cancer
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  • 19 Feb, 2024
Retrospective Chart Review Study of Patients With PIK3CA-Related Overgrowth Spectrum Who Have Received Alpelisib

Patient-level data are abstracted from medical charts of all eligible patients at all participating sites. Information from patients treated with alpelisib will be used to describe the efficacy and safety of alpelisib in PROS patients.

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  • 19 Feb, 2024