abiraterone Clinical Research Trials

Found 6 clinical trials

Featured trial

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Includes pre-screening
Phase 1
For Females
Family Medicine
Recruiting

Test Website pdf

test

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09 Aug, 2024
1 location

Multi-country trial
Phase 3
For Seniors
For adults
Recruiting in 1000s
Interventional Study
For Males
Recruiting

Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency

This study will assess the efficacy and safety of capivasertib plus abiraterone (+prednisone/prednisolone) plus androgen deprivation therapy (ADT) versus placebo plus abiraterone (+prednisone/prednisolone) plus ADT in participants with mHSPC whose tumours are characterised by PTEN deficiency.

steroid therapy

soft tissue lesion

bone metastases

prednisone

solid tumour

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19 Feb, 2024

Includes pre-screening
Phase 3
For Seniors
For adults
Recruiting in 100s
Interventional Study
all
Recruiting

Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine in Infants and Toddlers When Administered Concomitantly With Routine Pediatric Vaccines in the United Kingdom

The primary objective of the study is to demonstrate the non-inferiority of the antibody responses to meningococcal serogroups A, C, W, and Y in terms of hSBA vaccine seroprotection (antibody titer ≥ 1:8) when MenACYW conjugate vaccine is administered concomitantly with Bexsero® in the second year of life compared to …

Accepts healthy volunteers

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19 Feb, 2024
12 locations

Includes pre-screening
Phase 1
all
Recruiting

A081801 / RLUN20119 / ALCHEMIST-IO (ACCIO) / Yuhchyau Chen

This phase III ALCHEMIST trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and …

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19 Feb, 2024
1 location

Phase 3
For Seniors
For adults
Recruiting in 100s
Interventional Study
For Males
Recruiting

Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC

This is a Phase 3, multi-center, randomized, open-label, controlled study designed to evaluate the safety and efficacy of cabozantinib given in combination with atezolizumab versus a second novel hormonal therapy (NHT) in men with metastatic castration-resistant prostate cancer (mCRPC) who have previously been treated with one, and only one, NHT …

prostate adenocarcinoma

medical castration

lymphadenopathy

progressive disease

prednisone

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19 Feb, 2024

Phase 1
For Seniors
For adults
Recruiting in 10s
Interventional Study
For Males
Family Medicine
Recruiting

Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CC-94676 in Subjects With Metastatic Castration-Resistant Prostate Cancer

This is a first in human study to assess the safety, tolerability, PK, PD and preliminary efficacy of CC-94676 in men with progressive metastatic castration-resistant prostate cancer.

androgens

gonadotropin

castration-resistant prostate cancer

luteinizing hormone

enzalutamide

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19 Feb, 2024