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Found 3 clinical trials
NUVOLA TRIAL Open-label Multicentre Study

Around 15-25% of ovarian cancer (OC) patients carry germ-line mutation in BRCA1 or BRCA2 genes. Recent evidences showed that OC women with germline BRCA1/2 mutations (gBRCAmut) have an improved survival and higher platinum-sensitivity compared to BRCA1/2 naive (BRCAwt).

cytoreductive surgery
treatment and maintenance
liver metastasis
non-melanoma skin cancer
estimated creatinine clearance
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  • 19 Feb, 2024
Screening of Genetic Susceptibility Genes for Breast Cancer Patients in Chinese Communities

It is planned to take the community as the unit to inform and collect the breast cancer patients who voluntarily participate to carry out the detection of BRCA1, BRCA2, PTEN, CHEK2 and PALB2 genes through the community health service center.

CHEK2
BRCA2
BRCA1
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  • 19 Feb, 2024
Evaluating Cascade Communication Methods

Hereditary cancer programs face challenges with respect to effective communication of genetic test results within families and uptake of genetic testing by relatives. This study aims to determine if a "disclosure toolkit" provided to the index participant (carrier of cancer risk gene mutation) contributes to sharing genetic test results with …

genetic testing
hereditary cancer
cancer
genetic test
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  • 19 Feb, 2024