Found 996 clinical trials
Treatment of Pregnant Women With OUD
The investigators are testing two models of support for pregnant women with an opioid use disorder (OUD)
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- 19 Feb, 2024
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients
Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …
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- 19 Feb, 2024
No Opioids PrescrIptions On Discharge After Surgery
The goal of the study to eliminate the use of outpatient opioids prescriptions after major urologic surgery.
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- 19 Feb, 2024
Liberal vs. Restricted Post-discharge Opioid Prescribing Following Midurethral Sling
The specific objective of this proposal is to evaluate pain and opioid use following a midurethral sling (MUS) under two different opioid prescribing schemes. The central hypothesis is that, in spite of the fact that opioids are often routinely prescribed by many surgeons following this procedure, most patients do not …
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- 19 Feb, 2024
Buprenorphine for Cancer Pain
This study will evaluate patients on both buprenorphine and full agonist opioids (FAO) to assess for withdrawal symptoms. Patients will be evaluated by clinicians and using validated tools to assess for pain and withdrawal.
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- 13 Jan, 2025
Ketamine Analgesia in Third Molar Surgery
A reduction of morphine (opioid) use is sought because of side effects and the dependency risk. An effective alternative to opioids is ketamine, which lacks the side effects of opioids but provides powerful analgesic effects. METHOD At the start of surgery, Ketamine or placebo will be given in a vein …
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- 19 Feb, 2024
Perioperative Pain and Delirium in Geriatric Patients With Hip Fracture
The objective of this trial will be to establish whether the ultrasound-guided suprainguinal fascia iliaca compartment block is capable of protecting geriatric patients with hip fracture from delirium as compared to placebo
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- 19 Feb, 2024
A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation
We are going to evaluate the difference between perioperative intravenous steroid supplementation, perioperative periarticular steroid supplementation, and standard anaesthesia protocols. We'll evaluate the outcome of patients with knee osteoarthritis who are undergoing Total Knee Arthroplasty to understand which of the three treatments give more benefits to the patient.
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- 19 Feb, 2024
Effect of Academic Detailing to Reduce Opioid Prescribing in Dentistry
The purpose of this project is to improve quality of care for dental patients in the state of Michigan. This will be achieved through educating dentists about best practices for opioid prescribing and includes three continuing education (CE) credits and one (or two) academic detailing (AD) visits. The cohort of …
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- 19 Feb, 2024
Intervening With Opioid-Dependent MothersMothers and Infants
This study will assess the efficacy of the modified Attachment and Biobehavioral Catch-Up (mABC) Intervention, adapted for use with peripartum mothers receiving medication-assisted treatment for opioid use disorder. The investigators expect that mothers who receive the modified Attachment and Biobehavioral Catch-up Intervention will show more nurturing and sensitive parenting and …
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- 19 Feb, 2024