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Found 966 clinical trials
Azacitidine Combined With Chidamide in the Treatment of Newly Diagnosed PTCL Unfit for Conventional Chemotherapy

This prospective, open-label, single-arm study will evaluate the efficacy and safety of azacitidine in combination with chidamide in treatment of newly diagnosed peripheral T-cell lymphoma unfit for conventional chemotherapy.

measurable disease
tucidinostat
pet/ct scan
t-cell lymphoma
chidamide
  • 0 views
  • 19 Feb, 2024
  • 1 location
Anti-PD-1 Antibody Combined With Peg-Asparaginase and Chidamide for the Early Stage of NK/T Cell Lymphoma

This prospective pilot study to evaluate the efficacy and safety of the anti-PD-1 antibody combine with Peg-asparaginase and Chidamide regimen for stage IE and IIE ENKTL.

serum bilirubin
positron emission tomography
measurable disease
frontal sinus
renal function
  • 0 views
  • 19 Feb, 2024
  • 1 location
CPI-613 in Combination With Bendamustine in Patients With Relapsed/Refractory T-Cell Non-Hodgkin Lymphoma

The purpose of this study is to determine if it is possible to give CPI-613 with the drug Bendamustine for 2 days every 28 days without causing severe side effects. In addition, this study will also test the safety of CPI-613 when given in combination with Bendamustine.

cutaneous t cell lymphoma
non-hodgkin lymphoma
metastatic cancer
renal function test
measurable disease
  • 0 views
  • 19 Feb, 2024
  • 1 location
Lenalidomide in Combination With CHOP in Patients With Untreated PTCL

The prognosis of PTCL (except early stage ALK+ ALCL) is dismal. Previous study showed that single agent lenalidomide showed promising therapeutic activity in patients with relapsed or refractory PTCL. The investigators therefore design this phase II study to investigate the safety and efficacy of lenalidomide in combination with CHOP in …

anaplastic large cell lymphoma
peripheral t-cell lymphoma
lenalidomide
  • 0 views
  • 19 Feb, 2024
  • 1 location
Predictive Value of a SNP Signature and Liquid Biopsy in Natural Killer T-cell Lymphoma

The purpose of this study is to determine the Predictive value of a SNP signature and liquid biopsy in patients with natural killer T-cell lymphoma.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Comprehensive Genomic Profiling and Next Generation Functional Drug Screening for Patients With Aggressive Haematological Malignancies

EXALT-2 is a prospective, randomized, three arm study for treatment decision guided either by either comprehensive genomic profiling, next generation drug screening or physician's choice

melanoma of the skin
basal cell carcinoma of the skin
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location