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Found 110 clinical trials
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  • 19 Feb, 2024
  • 2 locations
A081801 / RLUN20119 / ALCHEMIST-IO (ACCIO) / Yuhchyau Chen  

This phase III ALCHEMIST trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and …

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  • 19 Feb, 2024
  • 1 location
Phase 1/2 Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 in Pediatric Subjects With MMA (reiMMAgine)

Detailed Description:MMA is a rare inborn error of branched chain amino acid metabolism. Despite strict dietary adherence and vigilant monitoring and care, affected individuals have recurrent episodes of severe illness and develop complications from different organ systems that can be life-threatening. Liver transplants can help, but gene transfer therapy could …

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  • 19 Feb, 2024
  • 1 location
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  • 19 Feb, 2024
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  • 19 Feb, 2024
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  • 19 Feb, 2024
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  • 19 Feb, 2024
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  • 24 Apr, 2024
  • 1 location