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Found 1297 clinical trials
Biomarkers in Rheumatoid Arthritis Treated With Anti-interleukin-6 Therapy

In patients suffering from rheumatoid arthritis, usual and experimental biomarkers will be assessed at D0, D15, W24 and W52 from the introduction of anti-IL-6 therapy, or during an intercurrent infection. Investigators thus hypothesized that experimental biomarker levels will still be increased at D15, contrary to usual biomarkers dependant on IL-6 …

rheumatism
inflammatory disorder
interleukin
arthritis
tocilizumab
  • 0 views
  • 19 Feb, 2024
Preoperative Estimation Of Disc Herniation Recurrence In Patients With Lumbar Disc Herniation

It is expected to enroll 350 patients aged 18-70 with lumbar disc herniation. Risk estimation of disc herniation recurrence will be evaluated preoperatively, then patient will undergo conventional microdiscectomy. Postoperative eximanation will include Visits every 6-months during 3 years to evaluate clinical outcomes.

  • 0 views
  • 19 Feb, 2024
Deciphering AMD by Deep Phenotyping and Machine Learning- Prospective Study - PINNACLE

We will conduct a prospective non-interventional study including 400 early AMD patients (=600 untreated early AMD eyes, including both unilateral (AREDS IV) and bilateral (AREDS II)) over 3 years to specifically investigate the morphological sequence of events preceding the conversion towards late AMD. All patients will be followed by OCT …

geographic atrophy
drusen
atrophy
neovascularization
mydriasis
  • 0 views
  • 19 Feb, 2024
Prospective Natural History Study of Smoking Immune Cell Profiles Epigenetics and COVID-19

At the first visit, participants will have blood tests. Blood will be drawn through a needle in an arm vein. They will provide a saliva sample in a container. Their height and weight will be taken. They will complete questionnaires about their medical history and smoking status.

social interaction
blood test
covid-19
body mass index
  • 0 views
  • 19 Feb, 2024
Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy

Our objective in this pilot study will be to identify PA parameters that can distinguish benign vs. malignant lesions, and also, if PA parameters change with within breast tumors during chemotherapy treatment over time.

breast mass
advanced breast cancer
HER2
breast neoplasm
locally advanced breast cancer
  • 0 views
  • 19 Feb, 2024
Describing Chinese Herbal Medicine Telehealth Care for Symptoms Related to Infectious Diseases Such as COVID-19

The purpose of the study is to design and execute a prospective, longitudinal, descriptive cohort study in a pragmatic clinical practice for adults with symptoms that may be related to COVID-19.

dyspnea
cough
covid-19
nausea
fever
  • 0 views
  • 19 Feb, 2024
BIOPSY SCANNER LLTECH Technology for Diagnosis of Breast Cancer

Based on this study, an atlas on breast lesions could be created to allow a broader evaluation of this technology in daily practice in diagnostic of breast pathology.

breast imaging reporting and data system
biopsy of breast
immunohistochemistry
  • 0 views
  • 19 Feb, 2024
Noncoding RNAs in COVID-19 and COVID-19 Related Kidney Dysfunction

In this study, critically ill patients with highly suspected or confirmed COVID-19 will be included. Main goal is the identification of noncoding RNAs in COVID-19 associated organ dysfunction with an emphasis on acute kidney injury.

kidney injury
critically ill
acute renal failure
covid-19
critical illness
  • 0 views
  • 19 Feb, 2024
Breaking the Bad News to the Bereaved Family and Their Reactions

The demographic characteristics, satisfaction survey evaluations and emotional reactions of the relatives of the patients who are admitted to the intensive care unit and who have an expected mortality rate higher than 50% according to the Apache-2 scoring system will be investigated.

  • 0 views
  • 19 Feb, 2024
Clip Marker Placement in Primary Lesions of Breast Cancer Patients Receiving Neoadjuvant Therapy

The present prospective registry study aims to evaluate how often the intramammary Tumark Vision clip can be detected by ultrasound after completion of NST in patients with TNBC and HER2+ breast cancer and thus, in the case of pCR, how often the elaborate clipping with mammographic (stereotactic) guidance can be

  • 0 views
  • 19 Feb, 2024