Found 1094 clinical trials
Securing Access to Innovative Molecules in Oncology and Hematology for Children Adolescents and Young Adults
It involves collecting safety and efficacy data, under the actual conditions of use of medicines in children and adolescents, using a validated tool (VIGINOM) and relying on the network of Interregional pediatric oncology appeal organizations (OIR) identified by INCa since 2010 and responsible for the organization of Pluridisciplinary Pediatric Interregional …
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- 19 Feb, 2024
- 1 location
Gene Mutation Spectrum of Malignant Hyperthermia in China
In this study, case information and specimens of patients with malignant hyperthermia(MH) will be collected from all over China, and gene fragment analysis, sanger sequencing method and/or high-throughput whole-genome sequencing will be performed. The MH bioinformatics database will be established to find the pathogenic gene and mutation site of MH …
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- 19 Feb, 2024
- 1 location
The Wearing-off Phenomenon of Ocrelizumab in Patients With Multiple Sclerosis
The primary goal of this research is to study the prevalence of the wearing-off effect and possible risk factors for wearing-off symptoms in patients with multiple sclerosis using ocrelizumab with the use of questionnaires. Furthermore, the goal is to study whether patients receiving extended dosing of ocrelizumab experience more wearing-off …
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- 19 Feb, 2024
- 1 location
Genetic Basis of COVID-19 Infection
We will study genetic factors causing severe disease due to infection with SARS-COV-2 which may help to find targeted therapy
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- 19 Feb, 2024
- 1 location
Noncoding RNAs in COVID-19 and COVID-19 Related Kidney Dysfunction
In this study, critically ill patients with highly suspected or confirmed COVID-19 will be included. Main goal is the identification of noncoding RNAs in COVID-19 associated organ dysfunction with an emphasis on acute kidney injury.
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- 19 Feb, 2024
- 1 location
Characteristics of Critically Ill COVID 19 Patients
COVID19 is n outbreak with unpredictable outcome
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- 19 Feb, 2024
- 1 location
Foot/Ankle at 7T MRI
To evaluate standard clinical sequences for 7 Tesla MRI of the foot and/or ankle to improve detailed depiction of the complex anatomy of this region. To evaluate various pathologies of the foot and/or ankle (plantar plate tears, Morton neuroma, tendon tears, ligament tears etc.).
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- 19 Feb, 2024
- 1 location
Lumpectomy Specimen Margin Evaluation With Tomography and Structured Light Imaging
The purpose of this study is to test a new surgical imaging system called "Structured Light Imaging (SLI)." This system is designed to examine tissue removed during breast cancer surgery to see whether the tissue's edges contain cancer. The current standard of practice is to remove the breast tumor tissue …
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- 19 Feb, 2024
- 1 location
The Influence of Two Different CO2 Absorbers on Sevoflurane Consumption During Anaesthesia
Traditional sodalime CO2 absorbers are known to not only react with CO2 but also with sevoflurane. Therewith, a potentially harmful compound (compound A) is formed that can be nephrotoxic. In the United States, the sevoflurane manufacturer therefore recommends keeping the FGF (FGF) at >2.0 L min-1 if a sodalime CO2 …
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- 19 Feb, 2024
- 1 location
Microwave Ablation for Leiomyoma
This prospective observational study aims to evaluate the effectiveness and acceptability of percutaneous or vaginal ultrasound guided microwave ablation for the treatment of symptoms related to uterine fibroids. We will include 200 women.
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- 19 Feb, 2024
- 1 location