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Found 201 clinical trials
First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

Primary Objectives:

<ul>
  • Dose Escalation Part A: To determine the maximum tolerated dose (MTD) of SAR442085 administered as a single agent in patients with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose (RP2D) for the subsequent Expansion Part B
  • Dose Expansion Part B: To assess …

    proteasome inhibitor
    autologous hematopoietic stem cell transplant
    immunotherapeutic agent
    ixazomib
    cell transplantation
    • 0 views
    • 19 Feb, 2024
    • 8 locations
    Ipatasertib + Atezolizumab to Prevent Recurrence in TNBC

    This research study involves the following investigational drugs:

    <ul>
  • Ipatasertib
  • Atezolizumab
    • ul>

    HER2
    treatment regimen
    immunostimulant
    axillary lymph node dissection
    blood transfusion
    • 0 views
    • 19 Feb, 2024
    Cisplatin+Pembrolizumab+RT in Vulvar Cancer

    This research is being done to see how well the combination of a standard of care drug, investigational drug, and radiation therapy work against unresectable vulvar squamous cell carcinoma.

    This research study involves the following:

    <ul>
  • Cisplatin (standard of care drug)
  • Pembrolizumab (investigational drug)
  • Radiation Therapy (standard …

    endocrine therapy
    recurrent disease
    primary tumor
    metastasis
    blood transfusion
    • 0 views
    • 19 Feb, 2024
    Ibrutinib + Venetoclax in Untreated WM

    The names of the study drugs involved in this study are:

    <ul>
  • Venetoclax
  • ibrutinib
    • ul>

    cancer
    bone marrow biopsy
    platelet transfusion
    serum pregnancy test
    plasmapheresis
    • 0 views
    • 19 Feb, 2024
    Pilot Study of an Implantable Microdevice for Evaluating Drug Responses in Situ in Prostate Cancer

    The name of the study intervention involved in this study is:

    <ul>
  • Implantation of a MR-guided microdevice
    • ul>

    neutrophil count
    carcinoma
    prostatectomy
    • 2 views
    • 19 Feb, 2024
    Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

    The names of the study interventions involved in this study are:

    <ul>
  • Sacituzumab govitecan (IMMU-132)
  • Pembrolizumab (Keytruda; MK-3475)
    • ul>

    HER2
    immunostimulant
    cns disease
    metastasis
    neuropathy
    • 8 views
    • 19 Feb, 2024
    Genetic Testing for All Breast Cancer Patients (GET FACTS)

    The names of the study methods involved in this trial are/is:

    <ul>
  • Quantitative genetic counseling (discussion is guided by tables and graphs)
  • Standard genetic counseling
    • ul>

    cancer
    breast carcinoma
    genetic counseling
    breast cancer
    cancer diagnosis
    • 0 views
    • 19 Feb, 2024
    Dupilumab Asthma Sleep Study

    Primary Objective:

    To assess the effect of dupilumab on sleep

    Secondary Objectives:

    <ul>
  • To evaluate the effect of dupilumab on additional patient reported sleep outcomes
  • To evaluate the effect of dupilumab on objective sleep assessment
  • To evaluate the effect of dupilumab on asthma symptoms
  • To evaluate the effect …

    pulmonary function test
    eosinophil count
    polysomnography
    fractional exhaled nitric oxide
    forced expiratory volume
    • 0 views
    • 19 Feb, 2024
    • 10 locations
    Innovative Trial for Understanding the Impact of Targeted Therapies in NF2

    Embedded within the Master Study are individual drug substudies.

    <ul>
  • Investigational Drug Sub-study A: Brigatinib
    • ul>

    nf2 gene
    investigational therapy
    conventional mri
    meningiomatosis
    meningioma
    • 0 views
    • 19 Feb, 2024
    Open Label Dose Escalation Study for the Safety and Efficacy of STP705 in Adult Patients With isSCC

    ul>

    • 0 views
    • 19 Feb, 2024